Results 71 to 80 of about 10,910 (247)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Estabilidade da cor de agentes cimentantes utilizados para facetas cerâmicas [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2010O objetivo deste estudo in vitro foi avaliar a estabilidade da cor de diferentes agentes ...
Pinto, Greciana Bruzi Brasil
core
Objective: Debonding of dental veneers represents the most common problems faced the patient and the dentist. The aim of this study was to compare the bond strength of repeated bonding Glass ceramic Lithium Disilicate (LD) veneers and new veneers to
Sara Kazzaz, Salam Zahawi
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
El objetivo de este estudio fue evaluar el efecto de tres tasas de compresión (TC) en la morfología de grietas de debobinado en chapas de Eucalyptus nitens para la fabricación de tableros contrachapados.
Andrés Acevedo +3 more
doaj
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Objective: To evaluate the shade match, marginal adaptation and patient satisfaction of VITA ENAMIC multiColor anterior laminate veneers and compare it to that of IPS e.max CAD.
Nancy Sayed Abdel Aziz Abdel All Khalil +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The main objective of this study was to investigate the key mechanical properties of cross-banded laminated veneer lumbers (LVL-C) manufactured from blending veneers recovered from sub-optimal native forest spotted gum and plantation hoop pine logs.
Nguyen, Hoan +3 more
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