Results 81 to 90 of about 11,226 (259)
Advanced Science, EarlyView.Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai +9 more
wiley +1 more source
The Clot Thickens: Differential Coagulotoxic and Cardiotoxic Activities of Anguimorpha Lizard Venoms
Despite their evolutionary novelty, lizard venoms are much less studied in comparison to the intense research on snake venoms. While the venoms of helodermatid lizards have long been assumed to be for defensive purposes, there is increasing evidence of ...
Jeremie Tai-A-Pin +5 more
core +1 more source
Knowledge about Snake Venoms and Toxins from Colombia: A Systematic Review
, 2023 Colombia encompasses three mountain ranges that divide the country into five natural regions: Andes, Pacific, Caribbean, Amazon, and Orinoquia. These regions offer an impressive range of climates, altitudes, and landscapes, which lead to a high snake ...
Jaime Andrés Pereañez +2 more
core +1 more source
Advanced Science, EarlyView.B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu +4 more
wiley +1 more source
Animal Venoms for Drug Discovery: A Constantly Evolving Research Field
Animal venoms, complex mixtures of molecules refined over thousands of years of evolution, represent far more than a simple defense or predatory system in venomous animals.
Mohamad Rima +5 more
core +1 more source
Advanced Science, EarlyView.Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley +1 more source
Cell-Penetrating Peptides Derived from Animal Venoms and Toxins
, 2021 Cell-penetrating peptides (CPPs) comprise a class of short polypeptides that possess the ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate across plasma membranes and accumulate in the cell cytoplasm ...
Gandhi Rádis-Baptista
core +1 more source
Thermodynamics and Kinetics in Host Design for Dendrite‐Free Zinc Metal Anodes
Advanced Science, EarlyView.This review comprehensively summarizes recent advances in host design strategies for high‐performance zinc metal anodes, and deeply elucidates their thermodynamic and kinetic design principles from the perspective of surface modification, interface engineering, and spatial confinement.
Peng Xiao Sun +9 more
wiley +1 more source
Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon
Toxicon: X, 2019 In the present work, venoms from five species of the genus Agkistrodon were evaluated in terms of their enzymatic (Phospholipase A2 and caseinolytic) and biological (edema forming, hemorrhagic, procoagulant and lethal) effects.
Luis Román-Domínguez +8 more
doaj +1 more source
Rapid Identification of Phospholipase A2 Transcripts from Snake Venoms [PDF]
, 2019 Phospholipase A2 (PLA2) is a major component in snake venoms and it is found in many different isoforms. To identify transcripts encoding different PLA2 isoforms, we developed a simple, rapid procedure.
Mendez, Bianca +9 more
core +1 more source