Results 271 to 280 of about 118,433 (329)

Biocompatible Mesoporous Materials for Bone Therapy

open access: yesAdvanced Science, EarlyView.
Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu   +6 more
wiley   +1 more source

300 HIGH PREVALENCE OF VENOUS INSUFFICIENCY IN PATIENTS WITH KNEE OSTEOARTHRITIS

open access: bronze, 2009
C. Orellana   +4 more
openalex   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan   +6 more
wiley   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

open access: yesAdvanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang   +21 more
wiley   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Energy Deficiency‐Induced ATG4B Nuclear Translocation Inhibits PRMT1‐Mediated DNA Repair and Promotes Leukemia Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrated that ATG4B translocates from the cytoplasm to the nucleus during energy deficiency. Nuclear ATG4B inhibits DNA repair by interacting with PRMT1. The nuclear ATG4B‐mediated DNA repair defect is significantly exacerbated within acute myeloid leukemia (AML) cells, promoting leukemia progression in an AML mouse model.
Zhenkun Wang   +20 more
wiley   +1 more source

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