Results 31 to 40 of about 64,935 (283)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Stasis Leg Ulcers: Venous System Revises by Triggered Angiography Non-Contrast-Enhanced Sequence Magnetic Resonance Imaging

Diagnostics, 2020
Objectives: The distribution of venous pathology in stasis leg ulcers is unclear. The main reason for this uncertainty is the lack of objective diagnostic tools.
Chien-Wei Chen, Yuan-Hsi Tseng, Min Yi Wong, Chao-Ming Wu, Bor-Shyh Lin, Yao-Kuang Huang   +5 more
doaj   +1 more source

Dermato-Lymphangitis in Filariasis Resembles Infected Chronic Venous Insufficiency: Two Case Reports and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2018
Chronic lower limb swelling is frequently encountered in clinical practice. Secondary lymphoedema and chronic venous insufficiency are two frequent causes of chronic lower limb swelling.
Dwijesh Kumar Panda, Devi Prasad Mohapatra   +1 more
doaj   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

DOPPLER ULTRASOUND AND PHOTOPLETHYSMOGRAPHY IN THE DIAGNOSISOF CHRONIC VENOUS INSUFFICIENCY

Zdravniški Vestnik, 2008
BACKGROUND CEAP classification of venous diseases included the clinical, etiological, anatomic,and pathophysiological mechanisms of chronic venous insufficiency.
Blaž Mlačak, Ivka Branimir, Tatjana Gazvoda, Danica Rotar Pavlič   +3 more
doaj  

Endovenous thermal ablation of superficial truncal veins and compression therapy result in symptom relief in venous valve aplasia

Journal of Vascular Surgery Cases and Innovative Techniques, 2023
Venous valve aplasia (or valvular rarefication) is a rare cause of chronic venous insufficiency. In the present report, we have described the case of a 33-year-old man with severe symmetric lower leg edema and heaviness and pain in both lower legs ...
Julia Deinsberger, MD, Oliver Schlager, MD, Christoph Sinz, MD, Benedikt Weber, MD, PhD   +3 more
doaj  

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

Chronic Cerebrospinal Venous Insufficiency and Multiple Sclerosis

İstanbul Medical Journal, 2018
Multiple sclerosis (MS) is a chronic inflammatory disease of unknown pathogenesis that causes demyelination of the central nervous system. Its cause currently remains unclear, but the underlying etiology is generally considered to be immunologically ...
Kadihan Yalçın Şafak
doaj   +1 more source

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

US duplex findings in chronic venous insufficiency of the lower limbs in 500 Mexican patients

Journal of the Mexican Federation of Radiology and Imaging
Introduction: There are few reports of ultrasound (US) duplex findings in patients with chronic venous insufficiency (CVI). The aims of this study were (1) to describe CVI ultrasound findings of the lower limbs in Mexican patients according to sex and ...
Mauricio Figueroa-Sanchez, M. Fernanda Lopez-Mendoza, Simmons D. Gough, J.M. Ignacio Lopez-Mendez   +3 more
doaj   +1 more source