Results 41 to 50 of about 118,433 (329)

Heinz-Lippmann disease as an underrecognized cause of chronic venous insufficiency-associated cutaneous ulcers: Clinical and imaging findings

Radiology Case Reports, 2020
Venous insufficiency is a frequent cause of consultation in primary care settings. Heterotopic ossification, consisting of an abnormal formation of true bone in extraskeletal soft tissues, is an underrecognized complication of chronic venous ...
Agustí Toll, MD, Salvatore Marsico, MD, Ivan Camilo Garcia Duitama, MD, Daniel López-Aventín, MD, Anna Agustí Claramunt, MD, Ramon Maria Pujol, MD, Jesus Ares-Vidal, MD, Albert Solano López, MD   +7 more
doaj   +1 more source

Halting Progression of Stasis Dermatitis: Community Perspectives and Strategies for Prevention [PDF]

, 2018
Complications of stasis dermatitis including venous ulcers, osteomyelitis, and cellulitis all significantly increase morbidity and mortality of disease.
Robbins, Allison B
core   +1 more source

Intraoperative Indocyanine Green Laser Angiography in Pediatric Autologous Ear Reconstruction. [PDF]

, 2016
Skin flap vascularity is a critical determinant of aesthetic results in autologous ear reconstruction. In this study, we investigate the use of intraoperative laser-assisted indocyanine green angiography (ICGA) as an adjunctive measure of skin flap ...
Bradley, James P, Farias-Eisner, Gina, Hoang, Han, Lee, Justine C, Mandelbaum, Rachel S, Martins, Deborah B   +5 more
core   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

Risk marker associations with venous thrombotic events: a cross-sectional analysis. [PDF]

, 2014
ObjectiveTo examine the interrelations among, and risk marker associations for, superficial and deep venous events-superficial venous thrombosis (SVT), deep venous thrombosis (DVT) and pulmonary embolism (PE).DesignCross-sectional analysis.SettingSan ...
Chan, Virginia T, Criqui, Michael H, Denenberg, Julie O, Golomb, Beatrice A, Koperski, Sabrina   +4 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Dermato-Lymphangitis in Filariasis Resembles Infected Chronic Venous Insufficiency: Two Case Reports and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2018
Chronic lower limb swelling is frequently encountered in clinical practice. Secondary lymphoedema and chronic venous insufficiency are two frequent causes of chronic lower limb swelling.
Dwijesh Kumar Panda, Devi Prasad Mohapatra   +1 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

May the Number of Pregnancies Predict the Progression and the Outcome of Venous Disease Treatment?

Diagnostics, 2023
Pregnancy is a well-known risk factor for venous insufficiency. However, even nulliparous women experience venous problems. Therefore, we aimed to assess the possible associations between the number of pregnancies, veins condition and treatment outcome ...
Justyna Wilczko, Cezary Szary, Anna Bodziony, Krzysztof Celejewski, Siavash Swieczkowski-Feiz, Marcin Napierala, Dominika Plucinska, Jerzy Leszczynski, Michal Zawadzki, Tomasz Grzela   +9 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source