Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells
Advanced Science, EarlyView.A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga +13 more
wiley +1 more source
Echocardiographic Assessment of the Pulmonary Venous Flow: An Indicator of Increased Pulmonary Flow in Congenital Cardiac Malformations [PDF]
, 2002 Iván Romero Rivera +3 more
openalex +1 more source
Molecular Creep Induced Fatigue Rupture of Fibrin Clots
Advanced Science, EarlyView.Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu +5 more
wiley +1 more source
Type II Abernethy Malformation in a Patient with Primary Budd-Chiari Syndrome
Annals of Hepatology, 2019 Budd-Chiari syndrome (BCS) is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction. Abernethy malformation is a congenital vascular malformation defined by diversion of portal blood away from the liver.
Peng-Xu Ding, Xin-Wei Han, Chao Liu
doaj
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Advanced Science, EarlyView.Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan +15 more
wiley +1 more source
Sclerotherapy, cryoablation, and surgical fixation of an intraosseous tibial venous malformation. [PDF]
Radiol Case Rep, 2023 Brown MA +4 more
europepmc +1 more source
A Wearable In‐Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood
Advanced Science, EarlyView.MenstruAI integrates a paper‐based biosensor into sanitary pads to detect biomarkers in menstrual blood, enabling accessible, lab‐free diagnostics health. The platform supports early disease detection, especially in underserved communities, while challenging menstrual stigma and opening pathways for scalable, inclusive, and sustainable population ...
Lucas Dosnon +3 more
wiley +1 more source
Recognition and Treatment of Venous Malformations of the Rectum
, 1996 David J. Keljo +3 more
openalex +1 more source
Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications
Advanced Science, EarlyView.Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar +15 more
wiley +1 more source
Multifocal Cerebral Venous Malformations and Associated Developmental Venous Anomalies in a Case of Blue Rubber Bleb Nevus Syndrome [PDF]
, 2003 Jae In Chung, H. Álvarez, P. Lasjaunias
openalex +1 more source