Results 91 to 100 of about 281,667 (252)

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Walsh & Hoyt: Intracranial Venous Malformations (Developmental Venous Anomalies, Venous Angiomas)

, 2005
Most intracranial venous malformations are supratentorial and commonly frontal, although they may occur in the cerebellum, brainstem, or even within or adjacent to the anterior visual sensory ...
Andrew Lee, MD
core  

Foam Sclerotherapy of Venous Malformations

, 2007
Venous malformations may occur either as localized or segmental lesions. Radiologic imaging defines the extent of involvement but magnetic resonance imaging is the best modality: it gives a bright hypersignal on T2-weighted spin-echo sequences.
J Bergan, V Cheng
core   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Walsh & Hoyt: Intracranial Venous Malformations

, 2005
Most intracranial venous malformations are supratentorial and commonly frontal, although they may occur in the cerebellum, brainstem, or even within or adjacent to the anterior visual sensory ...
Andrew Lee, MD
core  

Orbital venous-lymphatic malformations (lymphangiomas) mimicking cavernous hemangiomas.

, 2001
PURPOSE: To illustrate that orbital venous-lymphatic malformations (lymphangiomas) may rarely simulate cavernous hemangiomas, METHODS: Retrospective case review.
SELVA D, BONAVOLONTA G, ROOTMAN J., STRIANESE, DIEGO   +3 more
core   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Venous anomalies as potentially lethal risk factors during ordinary catheterization

Veins and Lymphatics, 2015
Venous malformations are rare but possible findings too, constituting a further risk factor for central venous catheter procedures. Herein we describe a case of death because of an innominate vein perforation by a catheter that incidentally was tucked ...
Savino Occhionorelli, Sergio Gianesini, Lorenzo Marinelli, Marianna Daniele, Sara Chierici, Paolo Zamboni   +5 more
doaj   +1 more source

Venous Malformations of the Head and Neck.

, 2018
Venous malformations (VMs) of the head and neck arise from deficits in the development of venous network. Clinically, VMs are highly variable, from small and asymptomatic varicosities to massive cervicofacial lesions.
Boon, Laurence M., Seront, Emmanuel, Emmanuel Seront, Vikkula, Miikka, Laurence M. Boon, Miikka Vikkula   +5 more
core   +1 more source