Systemic Bevacizumab for Severe Bleeding From Acquired Gastrointestinal Vascular Malformations
Targeted antiangiogenic therapy with systemic bevacizumab for bleeding from acquired GI VMs was found to be safe and effective for chronic and severe bleeding from acquired vascular malformations due to idiopathic angiodysplasia, chronic liver disease, and deficiencies of von Willebrand factor, in a patient population comprised mostly of heavily ...
Nardeen E. Ayad +5 more
wiley +1 more source
Water exchange across the blood-CSF barrier: A systematic review. [PDF]
Hjørnevik T, Eide PK.
europepmc +1 more source
We report a novel embolus‐induced PE rat model prepared via the inferior vena cava under ultrasound guidance. The embolus employed featured a tubular plastic casing filled with thrombus. By minimizing the contact surface between plasmin and thrombus, it effectively restrains the elevated plasmin activity in rats.
Huide Ma +7 more
wiley +1 more source
Combined Treatment of Hyperbaric Oxygen and Anti-vascular Endothelial Growth Factor Therapy in Cilioretinal Artery Occlusion Associated With Central Retinal Vein Occlusion. [PDF]
Brissos J +3 more
europepmc +1 more source
SnRNA‐seq reveals cellular heterogeneity and proliferation mechanisms in limb venous malformations
To dissect the cellular heterogeneity and invasive mechanisms of limb venous malformations (VMs), this study first obtained tissue samples from four patients with VMs and four normal controls (NC). Single‐nucleus suspension was prepared, followed by transcriptome library construction and sequencing. After pretreatment, quality control, standardization,
Junjie Lin +13 more
wiley +1 more source
Occludin-mediated barrier dysfunction and its role in cardiovascular and cerebrovascular pathogenesis. [PDF]
Xu W, Xu T, Long H, Jiang Q, Liao W.
europepmc +1 more source
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff +3 more
wiley +1 more source
Inflammation in Idiopathic Intracranial Hypertension: An Immunometabolic Mechanistic Framework and Clinical Implications. [PDF]
Han G +5 more
europepmc +1 more source
Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
A Woman's Infertility Journey Complicated by Severe Ovarian Hyperstimulation Syndrome - A Case Report. [PDF]
Khetani S, Hutchison J, Lee CM.
europepmc +1 more source

