Results 121 to 130 of about 4,775,633 (379)

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park   +7 more
wiley   +1 more source

Postoperative diastolic perfusion pressure is associated with the development of acute kidney injury in patients after cardiac surgery: a retrospective analysis

open access: yesBMC Nephrology, 2019
Background We aimed to investigate the relationship between the perioperative hemodynamic parameters and the occurrence of cardiac surgery-associated acute kidney injury.
Jifu Jin   +10 more
doaj   +1 more source

Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.

open access: yesGastroenterology, 2007
BACKGROUND AND AIMS Our aim was to identify predictors of clinical decompensation (defined as the development of ascites, variceal hemorrhage [VH], or hepatic encephalopathy [HE]) in patients with compensated cirrhosis and with portal hypertension as ...
C. Ripoll   +11 more
semanticscholar   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

Recollections of My Research in Developing the Heart-Lung Machine at Jefferson Medical College [PDF]

open access: yes, 2005
A personal memoir written by Dr. Bernard J. Miller about his introduction to and interest in medical research as well as his experiences working on the heart-lung machine. He focuses specifically on his working relationship with John H.
Miller, Bernard J.
core   +1 more source

Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise. [PDF]

open access: yes, 2015
Limb tissue and systemic blood flow increases with heat stress, but the underlying mechanisms remain poorly understood. Here, we tested the hypothesis that heat stress-induced increases in limb tissue perfusion are primarily mediated by local temperature-
Ali, L   +7 more
core   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Access via the internal jugular vein [PDF]

open access: yes, 2008
Central venous access via the internal jugular vein (IJV) is safe, relatively easy and very commonly used in infants and children undergoing cardiac surgery for congenital heart disease. Because of the wide range of anatomical variations an ultrasound-
Kruessell, Markus   +3 more
core  

Liquid‐Locked Bassanites for Scalable Fabrication of High‐Temperature Micro‐Supercapacitors Working at 300 °C

open access: yesAdvanced Functional Materials, EarlyView.
A “liquid locking” strategy is proposed and implemented for scalable printing of crack‐free bassanite ceramic frameworks with interlocking microstructures to host ionic liquids as effective electrolytes for high‐temperature micro‐supercapacitors (HT‐MSCs).
Shiqian Chen   +7 more
wiley   +1 more source

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