Results 101 to 110 of about 626,622 (390)

Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study

Journal of Immunology Research, 2022
Objective. Observational studies show the correlation between thyroid dysfunction and risk of venous thromboembolism. However, the causal effects remain uncertain. Our study was conducted to evaluate whether thyroid function and dysfunction were causally
Fushi Han, Chunyang Zhang, Miao Xuan, Zhuangli Xie, Kunming Zhang, Ying Li   +5 more
doaj   +1 more source

The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta‐analysis

Journal of Thrombosis and Haemostasis, 2020
Oncology guidelines suggest using the Khorana score to select ambulatory cancer patients receiving chemotherapy for primary venous thromboembolism (VTE) prevention, but its performance in different cancers remains uncertain.
N. van Es, M. Ventresca, M. Di Nisio, Qi Zhou, S. Noble, M. Crowther, M. Briel, D. Garcia, G. Lyman, F. Macbeth, Gareth Griffiths, A. Iorio, Mbuagbaw Lawrence, I. Neumann, J. Brożek, G. Guyatt, M. Streiff, Tejan Baldeh, I. Flórez, Ozlem Gurunlu Alma, G. Agnelli, W. Ageno, M. Marcucci, G. Bozas, G. Zulian, A. Maraveyas, B. Lebeau, R. Lecumberri, K. Sideras, C. Loprinzi, R. McBane, U. Pelzer, H. Riess, Ziad Solh, J. Perry, Lara A. Kahale, P. Bossuyt, C. Klerk, H. Büller, E. Akl, H. Schünemann   +40 more
semanticscholar   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

British Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl, Rod Hughes, Joachim Almquist, David Close, Jukka Mäenpää, Ulrika Tehler, Tina Jellesmark Jensen, Szilárd Nemes, Anne‐Kristina Mercier, Zala Jevnikar, Pablo Forte Soto, Dave Singh   +11 more
wiley   +1 more source

Simple measures can improve care in our hospitals : an audit of venous thromboembolism practice [PDF]

, 2013
: Venous thromboembolism (VTE) is a serious but preventable complication of hospitalisation. Doctors still sometimes fail to adhere to them, thus putting patients at risk and incurring considerable expense for the national health service.
Azzopardi, Stephanie, Busuttil, Sarah, Cordina, John, Lofaro, Thomas   +3 more
core  

Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study [PDF]

, 2005
Combined oral contraceptives,oral hormone replacement therapy and thrombophilias are recognised risk factors for venous thromboembolism in women.The objective of this study was to assess the risk of thromboembolism among women with thrombophilia who are ...
Brenkel, I., Clark, P., Greaves, M., Greer, I.A., Langhorne, P., Lowe, G.D.O., Regan, L., Robertson, L., Twaddle, S., Walker, I.D., Wu, O.   +10 more
core   +1 more source

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients. [PDF]

, 2017
Study Design:Retrospective cohort study. Objectives:Describe the rate and risk factors for venous thromboembolic events (VTEs; defined as deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in adult spinal deformity (ASD) surgery.
Bess, Shay, Burton, Douglas, Diebo, Basel G, Hart, Robert, International Spine Study Group (ISSG), Iyer, Sravisht, Kelly, Michael P, Kim, Han Jo, Klineberg, Eric O, Lafage, Virginie, Mundis, Gregory M, Schwab, Frank, Sciubba, Daniel, Shaffrey, Christopher I, Smith, Justin S   +14 more
core   +1 more source

American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients.

Blood Advances, 2018
BACKGROUND Venous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk.
H. Schünemann, M. Cushman, Allison E. Burnett, S. Kahn, J. Beyer-Westendorf, F. Spencer, S. Rezende, N. Zakai, K. Bauer, F. Dentali, Jill Lansing, S. Balduzzi, A. Darzi, G. P. Morgano, I. Neumann, R. Nieuwlaat, J. Yepes-Nuñez, Yuan Zhang, W. Wiercioch   +18 more
semanticscholar   +1 more source

Venous thromboembolism in inflammatory bowel disease

World Journal of Gastroenterology, 2020
Patients with inflammatory bowel disease (IBD) are at an increased risk for venous thromboembolism (VTE). VTE events carry significant morbidity and mortality, and have been associated with worse outcomes in patients with IBD. Studies have suggested that
Kimberly Cheng, A. Faye
semanticscholar   +1 more source

The Prognostic Value of Troponin in Acute Pulmonary Embolism: A Systematic Review and Meta‐Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Acute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. Troponin elevation is increasingly used for risk stratification, but its prognostic utility remains variably reported across studies. To evaluate the prognostic value of troponin elevation in patients with acute PE, concerning short‐term mortality and ...
Ahmed T. Elmewafy, James Waller, Priyanth Alaguraja, Kishan Desor, Ibrahim Antoun   +4 more
wiley   +1 more source