Results 211 to 220 of about 475,313 (268)
Abstract Aim Antithrombin (AT), a plasma protein with anticoagulant properties, has a long‐standing medical history, primarily for treatment of congenital AT deficiency. Accumulated clinical experiences suggest AT is a potential anticoagulant for thrombotic diseases. This study aimed to clarify the effectiveness, safety, and clinical significance of AT
Shoichi Matsutani+2 more
wiley +1 more source
ABSTRACT Introduction Thrombophilia, a blood coagulation disorder, poses risks of venous thromboembolism (VTE). Coagulation assays may not be sufficient to assess VTE risk and global assays such as Rotational Thromboelastometry (ROTEM) may add valuable information.
Mazen Assar+5 more
wiley +1 more source
Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani+2 more
wiley +1 more source
The Effect of Chronic Kidney Disease on Adverse In‐Hospital Outcomes at Radical Prostatectomy
ABSTRACT Objective Radical prostatectomy (RP) may be a treatment option for prostate cancer in patients with chronic kidney disease (CKD). However, the effect of CKD on adverse in‐hospital outcomes after RP is not well known. Methods Descriptive analyses, propensity score matching (PSM), and multivariable logistic and Poisson regression models were ...
Fabian Falkenbach+19 more
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Abstract Background An increasing number of patients in Australia are taking direct oral anticoagulants for a variety of indications since their introduction in the treatment landscape. There has always been some concern about the optimal management approach in the setting of major and/or life‐threatening bleeding.
Sara Shu‐Ling Ng+4 more
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Abstract Aims Previous studies have shown the COVID‐19 pandemic was associated with reductions in volume across a spectrum of non‐SARS‐CoV‐2 hospitalizations. In the present study, we examine the impact of the pandemic on patient safety and quality of care. Design This is a retrospective population‐based study of discharge abstracts. Methods We applied
Steven Habbous+4 more
wiley +1 more source
Abstract Aims The longitudinal programme of research described in this paper seeks to generate knowledge about factors influencing the implementation of a system‐level intervention, the clinical nurse leader care model, involving nurses as leaders at the frontlines of care and the outcomes achievable with successful implementation.
Miriam Bender, Marjory (Micki) Williams
wiley +1 more source