Results 231 to 240 of about 101,068 (248)
AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl +11 more
wiley +1 more source
An international survey of clinician recommendations for physical activity after venous thromboembolism. [PDF]
Chan A +12 more
europepmc +1 more source
Neck‐vein thrombosis during spaceflight
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley +1 more source
Unravelling the role of TET2 in venous thromboembolism: insights into mechanisms and therapeutic implications. [PDF]
Bai Y +9 more
europepmc +1 more source
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff +2 more
wiley +1 more source
Perioperative venous thromboembolism salvage via VA-ECMO-bridged surgical thrombectomy: A case report. [PDF]
Hu D, Zhao H, Yu Y.
europepmc +1 more source
ABSTRACT Multi‐chamber intracardiac thrombi are a rare and high‐risk complication in dilated cardiomyopathy, even during sinus rhythm. This case highlights the associated dangers of hemodynamic compromise and systemic embolization. Management requires vigilant anticoagulation and close monitoring to balance thromboembolic and bleeding risks.
Eba Fufa +10 more
wiley +1 more source
The role of statins in mitigating venous thromboembolism incidence and severity. [PDF]
Merz LE, Barnes GD, Schaefer JK.
europepmc +1 more source
The Crucial Role of Tinzaparin in Managing Venous Thromboembolism in the Cancer Population. [PDF]
Mauriello A +8 more
europepmc +1 more source

