Results 41 to 50 of about 301,296 (304)

Incidence of thromboembolism and thromboprophylaxis in medical patients admitted to specialized hospital in Ethiopia using Padua prediction score

SAGE Open Medicine, 2022
Introduction: Venous thromboembolism is a major cause of mortality and morbidity among hospitalized patients and thromboprophylaxis is one of the key strategies to reduce such events.
Mulugeta Asmamaw, Wubet Hungnaw, Achenef Motbainor, Hanan Muzeyin Kedir, Tamrat Assefa Tadesse   +4 more
doaj   +1 more source

Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]

, 2014
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
Camm, AJ, Bounameaux, H, A. John Camm, Henri Bounameaux, Camm AJ, Bounameaux H   +5 more
core   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) [PDF]

, 2011
<p>Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle ...
Frölich Marijke, Marijke Frölich, Frölich, Margaret, Brown, E.A., Jukema J Wouter, Anton JM de Craen, Ford Ian, Ian Ford, Frolich, M., E Ann Brown, Slagboom, P. Eline, Freeman Dilys J, Greer Ian A, Ann Rumley, Rumley, A., David J Stott, Tobias, E.S., Greer, I.A., Slagboom P Eline, Ian A Greer, Gordon DO Lowe, Stott David J, P Eline Slagboom, Craen, A.J.M. de, de Craen, Anton J.M., Rumley, Ann, Allan Gaw, Freeman, D.J., Tobias, Edward S., Naveed Sattar, Ford, Ian, Brown E Ann, Gaw, A., Jukema, J.W., Lowe, G.D.O., Dilys J Freeman, Freeman, Dilys J., Sattar, N., Jukema, J. Wouter, Ford, I., Robertson, Michele, Sattar Naveed, Slagboom, P.E., Robertson, M., de Craen Anton JM, Robertson Michele, Brown, E. Ann, Michele Robertson, Tobias Edward S, J Wouter Jukema, Sattar, Naveed, Rumley Ann, Lowe Gordon DO, Edward S Tobias, Stott, D.J., Gaw Allan   +55 more
core   +2 more sources

Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Effectiveness and safety of apixaban vs warfarin among venous thromboembolism patients at high-risk of bleeding.

PLoS ONE, 2022
This study evaluated effectiveness and safety of apixaban versus warfarin among venous thromboembolism patients at high-risk of bleeding (defined as having at least one of the following bleeding risk factors: ≥75 years; used antiplatelet, NSAIDs, or ...
Alexander T Cohen, Janvi Sah, Amol D Dhamane, Theodore Lee, Lisa Rosenblatt, Patrick Hlavacek, Birol Emir, Allison Keshishian, Huseyin Yuce, Xuemei Luo   +9 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Reshaping medical education: Performance of ChatGPT on a PES medical examination

Cardiology Journal
BACKGROUND: We are currently experiencing a third digital revolution driven by artificial intelligence (AI), and the emergence of new chat generative pre-trained transformer (ChatGPT) represents a significant technological advancement with profound ...
Simona Wójcik, Anna Rulkiewicz, Piotr Pruszczyk, Wojciech Lisik, Marcin Poboży, Justyna Domienik-Karłowicz   +5 more
doaj   +1 more source