Results 221 to 230 of about 80,404 (289)

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

open access: yesAdvanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu   +11 more
wiley   +1 more source

Metabolic and population profiles of active subseafloor autotrophs in young oceanic crust at deep-sea hydrothermal vents. [PDF]

open access: yesAppl Environ Microbiol
Elkassas SM   +13 more
europepmc   +1 more source

Tri–Band and Dual–Response Smart Windows With Asymmetric Mid–Infrared Emissivity for Year–Round Energy Conservation

open access: yesAdvanced Science, EarlyView.
Our promising smart window exhibits exceptional optical properties, enabling the indoor temperature reduction of 12°C during summer and delivering the annual energy savings of 14.2%–24.4% across mid–to–low latitudes. ABSTRACT Building energy consumption accounts for 20%–40% of global energy usage, with windows among the least energy–efficient ...
Cheng Wang   +11 more
wiley   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Decoding microbial diversity, biogeochemical functions, and interaction potentials in red sea hydrothermal vents. [PDF]

open access: yesEnviron Microbiome
Altalhi S   +10 more
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Home - About - Disclaimer - Privacy