Results 221 to 230 of about 61,398 (311)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

A diagnostic challenge: unveiling chronic thromboembolic pulmonary hypertension in the absence of visible thrombi: a case report. [PDF]

Eur Heart J Case Rep
Phu Quy H, Doan Duc D, Nguyen Duc T.
europepmc   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan, Zung Fan Yuan, Chang‐Chih Kuo, Chun‐Chun Hsu   +3 more
wiley   +1 more source

Pulmonary Artery Intimal Sarcoma Mimicking Pulmonary Embolism: A Case Report. [PDF]

J Belg Soc Radiol
Van Den Berghe T, Mahieu R, Verstraete K.   +2 more
europepmc   +1 more source

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

MedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun, Jiachen Qu, Sheng Peng, Yanan Hu, Amity Eliaz, Glenn M. Chertow, Isaac Eliaz, Zhiyong Peng   +7 more
wiley   +1 more source

Beyond the trial data: why conservative oxygenation targets require nuanced implementation in pediatric critical care. [PDF]

Transl Pediatr
Shaik MA, Horvat C.
europepmc   +1 more source

Premixed Lidocaine With Fospropofol Disodium for Safety and Clinical Evaluation Regarding Paresthesia Upon Fospropofol Disodium Injection: A Preclinical Experimental Study and a Randomized Controlled Trial

MedComm, Volume 7, Issue 4, April 2026.
This study explored the effect of lidocaine premixing on fospropofol‐induced paresthesia. While the mixture of fospropofol (FP) and lidocaine (LD) proved chemically stable and safe in preclinical tests, clinical results from randomized controlled trial showed no reduction in paresthesia in FP+LD group compared with FP+NS group.
Bo Jiao, Xiaolin Xu, Ying Cui, Caiyi Yan, Liyun Deng, Dequan Zhong, Qing Yang, Jiqian Xu, Yi Liu, Xiaohui Sun, Mengqian Xu, Tao Liu, Hui Xu, Xuejiao Tang, Xiaoqin Luo, Peng Liang, Jin Liu, Chan Chen   +17 more
wiley   +1 more source

Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report. [PDF]

Front Med (Lausanne)
Musaj A, Tronchet L, den Uil C, Weller D.   +3 more
europepmc   +1 more source

Heterogeneity of Treatment Effect for Intra‐Aortic Balloon Pump Use Across Lactate Trajectories in Cardiogenic Shock Patients Supported by VA‐ECMO: An Analysis of the Chinese Extracorporeal Life Support Registry

MedComm, Volume 7, Issue 4, April 2026.
Lactate trajectories can stratify the mortality risk in patients with acute myocardial infarction‐related cardiogenic shock receiving VA‐ECMO and reflect heterogeneity of treatment effect for intra‐aortic balloon pump. ABSTRACT This study aimed to investigate the heterogeneity of treatment effect for intra‐aortic balloon pump (IABP) across various ...
Xiang‐Jie Duan, Bo Wang, Cheng‐Long Li, Wan Chen, Peng Ding, Jie‐Lian Zhu, Jun‐Wei Wang, Xiao‐Tong Hou, Hai‐Yan Yin, Wan‐Jie Gu   +9 more
wiley   +1 more source