Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
Interdisciplinary Medicine, EarlyView.A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges? [PDF]
Adv Sci (Weinh)Shen P +5 more
europepmc +1 more source
Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
Journal of Applied Toxicology, EarlyView.ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
wiley +1 more source
Multi-Step Apparent Temperature Prediction in Broiler Houses Using a Hybrid SE-TCN-Transformer Model with Kalman Filtering. [PDF]
Sensors (Basel)Zheng P, Zhang W, Gao B, Ma Y, Chen C.
europepmc +1 more source
Major Cybersecurity Breaches: Shaping Corporate Cybersecurity Policies and Closing the Gaps
Journal of Corporate Accounting &Finance, EarlyView.ABSTRACT As digitalization accelerates, cybercrime has intensified in both scale and impact over the past two decades. This study aims to critically examine major cybersecurity events, assess them through the lens of routine activity theory, examine insight from three other established criminological and organizational theories, and address central ...
Laura K. Rickett, Deborah Smith
wiley +1 more source
Quantitative Assessment of CFD-Based Micro-Scale Renovation of Existing Building Component Envelopes. [PDF]
Biomimetics (Basel)Pan Y, Zhong L, Xu J.
europepmc +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.This study integrates ISO 15189:2022 requirements with failure mode and effects analysis (FMEA) to establish a comprehensive risk management framework for multibrand total laboratory automation (TLA) systems. By combining quantitative operational data with expert evaluation, an objective and reproducible occurrence scoring strategy was developed ...
Mengqi Wei +5 more
wiley +1 more source
Evolutionary Integration and Glucocorticoid Regulation of the Respiratory System: Structure, Function, and Homeostatic Adaptation. [PDF]
Med Sci (Basel)Meduri GU, Torres A.
europepmc +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Upper‐airway morphology changes during breathing can be captured with cine 4D MRI. Active‐learning nnU‐Net reduces manual labeling while maintaining accuracy. Purpose For automatic upper airway segmentation on free‐breathing cine 4D MRI using active learning and quantifying dynamic changes under two mouth positions.
Cheng‐Yang Yu +7 more
wiley +1 more source
Predicting Do-Not-Resuscitate Decisions in Critically Ill Patients Through Using Multitask Learning: A Retrospective Study of the MIMIC-IV Database. [PDF]
InquiryLin MY, Yeh CF, Chao WC.
europepmc +1 more source