Results 201 to 210 of about 2,245,625 (286)

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Sedative medications: a potentially modifiable risk factor for improving neurocognitive outcomes after critical illness in infants and children. [PDF]

Front Pediatr
GaHyun Byeon A, Mir M, Jerath A, Slessarev M, Lalgudi Ganesan S, McKinnon NK.   +5 more
europepmc   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

A narrative review on the interplay between interstitial lung disease and obstructive sleep apnea: Mechanisms, clinical implications, and management strategies. [PDF]

Sleep Med X
Ocal N, Balcan B, Peker Y.
europepmc   +1 more source

Effects of Intubation Duration on Trachea: A Histopathological Study

The Laryngoscope, EarlyView.
This study evaluated the histopathological effects of prolonged endotracheal intubation on the human trachea using biopsy specimens obtained during tracheotomy. Prolonged intubation was associated with progressive inflammatory and structural changes, with tracheal dilatation and perichondritis increasing significantly after 14 days.
Osman Kilic, Serdal Celik, Cemal Gundogdu, Berina Slipcevic, Ayse Yasemin Gunduz, Hamdi Sirac Gundogdu, M. Tayyar Kalcioglu   +6 more
wiley   +1 more source

Intelligent decision-making for mine ventilation systems based on graph neural network and deep reinforcement learning fusion. [PDF]

Sci Rep
Zhang K, Yang X, Li H.
europepmc   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

The Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz, Nour Awad, Nicholas Russell, Juliana El Sheikh, Logan Obermeyer, Peter J. Larson, Yoonjee C. Park, Gregory R. Dion   +7 more
wiley   +1 more source

Extracellular matrix remodeling modifies structural responses to ventilator-induced lung injury: a multiscale correlative imaging study. [PDF]

Respir Res
Sagar MMR, D'Amico L, Deyhle RT, Meyer R, Fardin L, Mahmutovic Persson I, Cercos-Pita JL, Perchiazzi G, Köster S, Benke CV, Alves F, Tromba G, Olsson LE, Bayat S, Dullin C.   +14 more
europepmc   +1 more source

Machine Learning‐Based Risk Stratification Tool for Hearing Loss in High‐Risk Neonates

The Laryngoscope, EarlyView.
Machine learning models, particularly XGBoost, provide robust risk stratification for neonatal hearing loss by capturing complex interactions among clinical risk factors such as NICU stay duration and family history. To translate these predictive capabilities into routine practice, an open‐access web‐based clinical decision support tool was developed ...
Sevgi Kutlu, Emre Söylemez, Betül Temir, Esranur Ulusoy, Zahide Çiler Büyükatalay   +4 more
wiley   +1 more source

Effects of music therapy on delirium, clinical outcomes, and psychological and sleep outcomes in adult ICU patients: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Yuan Y, Wang S, Wang H, Wang W, Dai K.
europepmc   +1 more source