Results 251 to 260 of about 102,111 (310)

Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions

open access: yesExperimental Physiology, EarlyView.
Abstract Long‐duration spaceflight impacts essentially every system in the human body, resulting in multisystem deconditioning that might impair the health and performance of crewmembers, particularly on long‐duration exploration missions to Mars. In this review, we apply the sport science model of athlete monitoring, testing and training to astronauts;
Luke DeVirgiliis   +8 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Functional Lung Imaging Identifies Peripheral Ventilation Changes in ꞵ-ENaC Mice. [PDF]

open access: yesRespirology
Reyne N   +10 more
europepmc   +1 more source

Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats

open access: yesExperimental Physiology, EarlyView.
Abstract Obstructive sleep apnoea (OSA) is a prevalent cardiorespiratory disorder associated with significant neurocognitive consequences. Despite the higher prevalence of OSA in men, there is a strong association between OSA and Alzheimer's disease (AD), which disproportionately affects women.
Emily C. Cheung   +16 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen   +5 more
wiley   +1 more source

Seizure‐related death exhibits a circadian rhythm independent of seizure timing or sleep in a mouse model of Dravet syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sudden unexpected death in epilepsy (SUDEP) frequently occurs at night when humans are asleep. Nocturnal mouse models of seizure‐associated death also exhibit higher mortality during the night. This nighttime risk of death may be under the regulation of independent circadian and sleep state‐dependent processes.
Benjamin L. Kreitlow   +3 more
wiley   +1 more source

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