Results 51 to 60 of about 626,371 (315)

Natural Ventilation Enhancement of a Roof Solar Chimney with Wind-Induced Channel

Energies, 2022
A novel roof solar chimney with wind-induced channel was designed herein to augment indoor natural ventilation under combined action of wind and solar energy.
Ning Gao, Yao Yan, Rui Sun, Yonggang Lei
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Assessment of Indoor Air Quality for Group-Housed Macaques (Macaca spp.)

Animals, 2022
Indoor Air Quality (IAQ) is strongly associated with animal health and wellbeing. To identify possible problems of the indoor environment of macaques (Macaca spp.), we assessed the IAQ.
Annemiek Maaskant, Isabel Janssen, Inge M. Wouters, Frank J. C. M. van Eerdenburg, Edmond J. Remarque, Jan A. M. Langermans, Jaco Bakker   +6 more
doaj   +1 more source

Flow Rate Dependence of Ventilation [PDF]

Beiträge zur Tabakforschung International/Contributions to Tobacco Research, 1987
Abstract A quantitative model describing the effects of puffing conditions on the level of filter ventilation was developed and evaluated. The development of the model was based on a quadratic flow-pressure drop relationship which was validated with experimental measurements for numerous plug wraps, tipping papers, and combinations of ...
openaire   +1 more source

Modelling indoor air carbon dioxide concentration using grey-box models [PDF]

, 2017
Predictive control is the strategy that has the greatest reported benefits when it is implemented in a building energy management system. Predictive control requires low-order models to assess different scenarios and determine which strategy should be ...
Carnevali, Matteo, Casals Casanova, Miquel, Forcada Matheu, Núria, Gangolells Solanellas, Marta, Macarulla Martí, Marcel   +4 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Investigation on the Effect of Opening Size and Position on Wind-Driven Cross-Ventilation in an Isolated Gable Roof Building

Applied Sciences
In this study, the influence of window opening sizes and positions on wind-induced cross ventilation performance in an isolated gable roof building was numerically investigated using the k-ω SST turbulence model.
Hacımurat Demir, Burak Aktepe
doaj   +1 more source

Assessing ventilation rate measurements in a mechanically ventilated laying hen facility

Poultry Science, 2019
Gaseous emission in laying hen facilities affects animal production performance and the environment. Emission is ruled by gas concentration and ventilation rate (VR), which are the key parameters to estimate precise emission factors. In this work, VR were assessed in a mechanical ventilated laying hen facility under Mediterranean climate conditions ...
E Rosa, H Arriaga, S Calvet, P Merino
openaire   +3 more sources

Exercise-induced respiratory muscle work: Effects on blood flow, fatigue and performance [PDF]

, 2008
This is the post print version of this article. The official published version can be obtained from the link below.In healthy subjects, heavy intensity endurance exercise places substantial demands on the respiratory muscles as breathing frequency ...
C.A. Harms, D.E. O’Donnell, J.A. Dempsey, J.D. Miller, J.D. Miller, J.M. Hill, K.N. Stark-Leyva, L.M. Romer, M. Simon   +8 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source