Results 231 to 240 of about 323,472 (312)

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

Annals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones, Blessing Nyakutsikwa, Michael H. Askenase, Matthew Gittins, Mary Newland, Siobhan Crilly, Paul R. Kasher, Yvonne Davidson, Federico Roncaroli, Stuart M. Allan, Lauren H. Sansing, Wendy Ziai, Daniel F. Hanley, INFLAME‐ICH Investigators, Mark Harrigan, David Miller, Judy Huang, Wendy Ziai, Jack Jallo, Fred Rincon, Gaurav Gupta, Igor Rybinnik, Diederik Bulters, Mary Leigh Gelea, Andras Buki, Erzsebet Ezer, Hiren Patel, Adrian Parry‐Jones, Charles Matouk, Kevin Sheth / Lauren Sansing, Ali Zomorodi, Michael James, Pal Barzo, Krisztian Tanczos, Gregory Thompson, Ventatakrishna Rajajee/Aditya Pandey, Peter Nakaji, Shawn E. Wright, Walter Galicich, Thomas Bergman, Andrew Carlson, Huy Tran, Philipp Taussky, Safdar Ansari, Fuat Arikan, Marcelino Baguena, Ronald Reimer, W. David Freeman, Ania Pollack, John Terry, Geza Mezey, Katalin Szabo/Laszlo Csiba, Robert F. James, Steven J. Barrer, Larami MacKenzie   +54 more
wiley   +1 more source

Research on Evaporation Characteristics and Safe Storage Duration of Marine Liquid Hydrogen Storage Tanks Under the Coupling Effect of Heat Leakage and Sloshing

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Liquid hydrogen, a zero‐carbon and high–energy‐density fuel, is a promising option for future oceangoing vessels. During maritime transportation, onboard cryogenic tanks are exposed to ambient heat leakage and ship‐induced roll motion, which can trigger sloshing and fundamentally modify the coupled thermo‐fluid processes governing boil‐off and
Yan Deng, Wenfeng Wu, Zhenyu Zhao, Rongsheng Lin, Liangyi Sun, Youfei Liu   +5 more
wiley   +1 more source

Changing a Winning Team—Replacement of Brominated Flame Retardant and Antimony Trioxide in Acrylonitrile–Butadiene–Styrene

Journal of Applied Polymer Science, EarlyView.
This comprehensive study investigates reducing the amount of brominated flame retardant (Br) and/or antimony trioxide (ATO) in acrylonitrile–butadiene–styrene. Therefore, condensed‐phase flame‐retardant mechanisms are introduced into the flame‐inhibition system.
Sebastian M. Goller, Bernhard Schartel, Simone Krüger   +2 more
wiley   +1 more source

Real‐time monitoring of root dielectric properties for assessing crop plant damage caused by foliar application of glyphosate

Applications in Plant Sciences, EarlyView.
Abstract Premise There is a knowledge gap regarding how foliar injury and restricted water uptake can be detected by measuring root dielectric response. This pot study nondestructively evaluated the efficiency of real‐time dielectric measurement to monitor the effects of glyphosate spraying.
Imre Cseresnyés, Anna Füzy, Tünde Takács   +2 more
wiley   +1 more source

Design and Analysis of a Mechanical Ventilation System Based on Cams

, 2020
Calderón J, Rincón C, Agreda B, Jiménez JJ.   +3 more
europepmc   +1 more source

Functional models from limited data: A parametric and multimodal approach to anatomy and 3D kinematics of feeding in basking sharks (Cetorhinus maximus)

The Anatomical Record, EarlyView.
Abstract Basking sharks, Cetorhinus maximus (Gunnerus, Brugden [Squalus maximus], Det Kongelige Norske Videnskabers Selskabs Skrifter, 1765, vol. 3, pp. 33–49), feed by gaping their mouths and gill slits, greatly reorienting their cranial skeletons to filter food from water.
Tairan Li, Mike Schindler, Martha Paskin, Venkata A. Surapaneni, Elliott Scott, Sabine Hauert, Nicholas Payne, David E. Cade, Jeremy A. Goldbogen, Frederik H. Mollen, Daniel Baum, Sean Hanna, Mason N. Dean   +12 more
wiley   +1 more source

Osteological correlates of the respiratory and vascular systems in the neural canals of Mesozoic ornithurines Ichthyornis and Janavis

The Anatomical Record, EarlyView.
Abstract In birds, the neural canal houses a variety of anatomical structures including the spinal cord, meninges, spinal vasculature, and respiratory diverticula. Among these, paramedullary diverticula and the extradural dorsal spinal vein may leave behind osteological correlates in the form of pneumatic foramina and fossae, and a bilobed geometry of ...
Jessie Atterholt, M. Grace Burton, Mathew J. Wedel, Juan Benito, Ellen Fricano, Daniel J. Field   +5 more
wiley   +1 more source

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

The Anatomical Record, EarlyView.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman, Robert K. Carr, Kate Trinajstic, Zerina Johanson, Oleg A. Lebedev   +4 more
wiley   +1 more source