Results 21 to 30 of about 273,929 (243)

Ventilation System Design and the Coronavirus (COVID-19)

Frontiers in Built Environment, 2021
Most new office buildings in Nordic countries are equipped with balanced mechanical ventilation systems. The purpose of ventilation in office buildings is to provide thermal control by supplying cold or warm air for adequate indoor air quality.
Alireza Afshari, Göran Hultmark, Peter V. Nielsen, Alessandro Maccarini   +3 more
doaj   +1 more source

Simulation Study on Airflow Organization and Environment in Reconstructed Fangcang Shelter Hospital Based on CFD

Buildings, 2023
With frequent outbreaks of COVID-19, the rapid and effective construction of large-space buildings into Fangcang shelter hospitals has gradually become one of the effective means to control the epidemic. Reasonable design of the ventilation system of the
Yongwen Yang, Haitao Yang, Qifen Li, Liting Zhang, Ziwen Dong   +4 more
doaj   +1 more source

Experimental determination of the ventilation pressure thermal drop effect on the air flows in the inclined mine workings

Frontiers in Mechanical Engineering
The increasing use of mechanized facilities in underground mining operations, including conveyor systems, diesel and electric equipment, and rail transport, is driving the expansion into new mineral reserves, often accessed through inclined mine workings.
Lev Levin, Evgeniy Kuzminykh, Sergei Zhikharev   +2 more
doaj   +1 more source

Correlation between germ and particle measurements for the qualification of ventilation systems in the OR

Current Directions in Biomedical Engineering, 2017
Healthcare associated infections in surgical procedures have long been the focus of scientific research. In Germany, more than 225,000 patients suffer from such infections each year [1].
Bulitta Clemens, Walberer Laura, Buhl Sebastian   +2 more
doaj   +1 more source

Free field Active Noise Control system development using a 3D Finite Element based approach

Acta Acustica
This technical article presents a systematic methodology for efficient design, modeling, and validation of an Active Noise Control (ANC) system under free field conditions, aiming for global noise reduction.
Budnik Maximilian, Mees Valentin
doaj   +1 more source

Evaluation of Thermal Comfort Conditions in Retrofitted Facades Using Test Cells and Considering Overheating Scenarios in a Mediterranean Climate

Energies, 2018
Energy retrofitting of the housing stock is a priority in current regulatory standards as a means of reducing energy consumption. The strategies used in retrofitting housing stock ought to respond both to regulatory conditions and to two challenges ...
Carmen María Calama-González, Rafael Suárez, Ángel Luis León-Rodríguez, Samuel Domínguez-Amarillo   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Investigation of the Optimal Operating Position of an Air Cleaner in Terms of Indoor Air Quality in a Four-Bed Hospital Ward

Toxics, 2022
The use of air cleaners indoors has increased with the increase in indoor activities driven by the COVID-19 outbreak. In this study, the indoor air quality was determined at the location of each patient’s respirator in a four-bed hospital ward equipped ...
Jungsuk Lee, Su-Hoon Park, Ik-Hyun An, Young-Won Kim, Se-Jin Yook   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source