Results 51 to 60 of about 323,472 (312)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effects of vehicle ventilation system, fuel type, and in-cabin smoking on the concentration of toluene and ethylbenzene in Pride cars

International Journal of Environmental Health Engineering, 2013
Aims: This study aimed to evaluate the concentrations of toluene and ethylbenzene inside the Pride cars and to investigate the effects of the vehicle ventilation system, fule type, and interior smoking on their concentration.
Masoud Rismanchian, Massomeh Garsivaz, Hamidreza Porzamani, Mohammad Reza Maracy, Mahnaz Shakerian, Mohammad Heidari   +5 more
doaj   +1 more source

Effect of Ventilation System on Spread and Control of Infections (COVID-19) in Indoor Environments: Based on Current Studies

Asian Pacific Journal of Environment and Cancer, 2020
Transmission of infectious diseases like SARS-COV-2 by ventilation systems has become an international concern. In this study, an attempt was made to assess the role of ventilation systems in spread and control of SARS-COV-2 in indoor environments.
Mohammad Nourmohammadi, Ramezan Mirzaei, Ebrahim Taban, Saeed Yari   +3 more
doaj   +1 more source

Droplets Transmission Mechanism in a Commercial Wide-Body Aircraft Cabin

Applied Sciences, 2022
COVID-19 is a respiratory infectious disease that spreads readily between people, and an urgent issue of passengers’ exposure risk assessment in commercial aircraft has been raised because an aircraft cabin as a confined space may carry and transmit the ...
Benben Kong, Yitao Zou, Mengmeng Cheng, Hong Shi, Yanlong Jiang   +4 more
doaj   +1 more source

The vanishing threat: Stealthy malfunction of closed suction system

, 2023
This case report presents a rare case of a mechanical ventilation leak that was initially missed by clinicians in a patient with a myxoedema coma. Despite all efforts to investigate the causes of the leak, including a bedside lung ultrasound and chest ...
Sandeep Kumar, Qureshi, Faisal, Nikhil Kothari, Kothari, Nikhil, Kumar, Sandeep, Akshaya Kumar Das, Faisal Qureshi, Das, Akshaya   +7 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhage

, 2010
BACKGROUND: Both high tidal volume (VT) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung injury in infant rats exposed to severe hemorrhage.
Nicholls, Philip K., Sly, P.D., Hantos, Z, Sly, Peter D., Berry, L.J., Cannizzaro, V; https://orcid.org/, Hantos, Zoltán, Cannizzaro, V., Berry, Luke J., Nicholls, P.K., Hantos, Z., Nicholls, P K, Sly, P D, Berry, L J, Cannizzaro, Vincenzo   +14 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Eksperimentinio šilumos siurblio ciklo valdymo algoritmo paieška / Experimental study of the heat pump cycle control algorithm search

Mokslas: Lietuvos Ateitis, 2019
This paper analyzes an experimental heat pump used for heat recovery in a mechanical room ventilation system. The aim of the work is to examine the operation, control logic of the heat pump and evaluate the possibilities of its operation modes, cycle ...
Anton Frik, Dovydas Rimdžius, Tomas Kropas   +2 more
doaj   +1 more source

Impact of human–human virus transmission in an air-conditioned room with proper ventilation system

International Journal for Simulation and Multidisciplinary Design Optimization, 2022
As we are probably aware of certain infectious diseases that transmit from body to body because of perspiration or respiration of air from a human being containing strains of the infection, the goal of this investigation is to see how the infection is ...
Manas Chalumuru, Narasimha Raju Pusapati Laxmi, Bharat Kumar Kethavarapu Naga, Rajan Harish   +3 more
doaj   +1 more source