Results 91 to 100 of about 89,678 (292)

Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations [PDF]

open access: yes, 2017
Health care-associated infections (HAI) are a major public health problem with a significant impact on morbidity, mortality and quality of life. They represent also an important economic burden to health systems worldwide.
A Higgins   +113 more
core   +6 more sources

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

open access: yesiMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang   +13 more
wiley   +1 more source

Ventilator-associated pneumonia

open access: yesIntensive Care Medicine, 2022
Otavio T. Ranzani   +2 more
openaire   +3 more sources

Oral condition of critical patients and its correlation with ventilator-associated pneumonia: a pilot study

open access: yesRevista de Odontologia da UNESP
INTRODUCTION: Literature has reported inadequate oral hygiene conditions in Intensive Care Unit (ICU) patients and the occurrence of Ventilator-associated pneumonia in about 9%-27% of all intubated patients.
Andrea Carvalho De Marco   +5 more
doaj  

The importance of Clinical Research [PDF]

open access: yesHorizonte Médico, 2016
Objetives: to describe the clinical and epidemiological characteristics, evolution and to identify mortality factors associated in patients with snp.Material and methods: descriptive study of a serie of cases of the intensive care unit (icu) of a general
Frank Lizaraso Caparó   +1 more
doaj  

Ventilator-associated respiratory infection in a resource-restricted setting: impact and etiology

open access: yesJournal of Intensive Care, 2017
Background Ventilator-associated respiratory infection (VARI) is a significant problem in resource-restricted intensive care units (ICUs), but differences in casemix and etiology means VARI in resource-restricted ICUs may be different from that found in ...
Vu Dinh Phu   +29 more
doaj   +1 more source

Clinical and in vitro efficacy of colistin plus vancomycin and rifampin against colistin-resistant Acinetobacter baumannii causing ventilator-associated pneumonia [PDF]

open access: yes, 2017
We present the case of a patient with ventilator-associated pneumonia (VAP) caused by a pan-resistant Acinetobacter baumannii successfully treated with the combination colistin plus vancomycin plus rifampin, whose in vitro activity was investigated by ...
Cipolla, Alessia   +5 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

open access: yesInterdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang   +10 more
wiley   +1 more source

Mechanical ventilation in chronic obstructive pulmonary disease patients, noninvasive vs. invasive method (randomized prospective study) [Usporedba neinvazivne i invazivne umjetne ventilacije kod bolesnika s kroničnom opstruktivnom plućnom bolesti: prospektivna randomizirana studija] [PDF]

open access: yes, 2009
Acute respiratory failure due to chronic obstructive pulmonary disease (COPD) presents an increasing problem throughout the world. The aim of this study was to compare invasive and non-invasive mechanical ventilation (MV) for patients with COPD.
Buković, Damir   +5 more
core  

Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]

open access: yes, 2016
Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto   +1 more
core   +1 more source

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