Results 61 to 70 of about 8,207,494 (286)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Ventilator-associated pneumonia: the influence of bacterial resistance, prescription errors, and de-escalation of antimicrobial therapy on mortality rates

Brazilian Journal of Infectious Diseases, 2016
Ventilator-associated pneumonia is the most prevalent nosocomial infection in intensive care units and is associated with high mortality rates (14–70%).
Ana Carolina Souza-Oliveira, Thúlio Marquez Cunha, Liliane Barbosa da Silva Passos, Gustavo Camargo Lopes, Fabiola Alves Gomes, Denise Von Dolinger de Brito Röder   +5 more
doaj   +1 more source

Diagnosis dan Penatalaksanaan Ventilator-Associated Pneumonia [PDF]

, 2020
Abstrak Ventilator-associated pneumonia (VAP) atau pneumonia terkait penggunaan ventilator masih menjadi masalahdalam penatalaksanaan pasien pengguna ventilasi mekanis.
Boedi Swidharmoko, Anna Rozaliyani
core   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Experimental ventilator-associated pneumonia: distribution of lung infection and consequences for lung aeration

Brazilian Journal of Infectious Diseases, 2003
Ventilator-associated pneumonia (VAP) has been described in humans and in experimental animals. The most severe lesions are located in dependent lung segments along a sterno-vertebral axis, however the cephalocaudal distribution of lung infection remains
Vieira Silvia Regina Rios, Goldstein Ivan, Lenaour Gilles, Marquette Charles-Hugo, Rouby Jean-Jacques   +4 more
doaj  

Ventilator-associated pneumonia prevention in the Intensive care unit using Postpyloric tube feeding in China (VIP study): study protocol for a randomized controlled trial

Trials, 2022
Background Ventilator-associated pneumonia is a challenge in critical care and is associated with high mortality and morbidity. Although some consensuses on preventing ventilator-associated pneumonia are reached, it is still somewhat controversial.
Linhui Hu, Kaiyi Peng, Xiangwei Huang, Zheng Wang, Quanzhong Wu, Yumei Xiao, Yating Hou, Yuemei He, Xinjuan Zhou, Chunbo Chen   +9 more
doaj   +1 more source

Chlorhexidine: The Fight to End Ventilator-Associated Pneumonia [PDF]

, 2020
There is a major problem that affects patient outcomes in the hospital setting. This problem is ventilator-associated pneumonia. Ventilator-associated pneumonia is the second most nosocomial infection in critical care patients.
Gaspari, Jeremy
core   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

BMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai, Yifu Tan, Jiaheng Liang, Shen Liu, Jiabin Zhao, Shanbo Ma, Chunxin Liu, Minghua Du, Mark Selvan, Xiaopeng Shi, Liqiang Song, Peng Li   +11 more
wiley   +1 more source

Ventilator-Associated Pneumonia Bundle Care [PDF]

, 2021
Ventilator-associated pneumonia (VAP) is one of the most significant nosocomial infections in intensive care units (ICU) worldwide. Patients who have this infection due to lengthy hospital stays face excessive hospital expenditures and are forced to ...
Binnichan, Jeemole Kattezham
core   +2 more sources

Biventricular Pressure‐Volume Loop Analysis in an LVAD Patient Optimized With Impella RP Flex

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Right ventricular (RV) failure after left ventricular assist device (LVAD) implantation is a serious complication which may necessitate temporary mechanical support in refractory cases. Here we describe a 63‐year‐old man with end‐stage ischemic cardiomyopathy and severe combined pre‐ and post‐capillary pulmonary hypertension who developed ...
Sara S. Inglis, Serena Rahme, Andrew N. Rosenbaum, Atta Behfar   +3 more
wiley   +1 more source