Results 191 to 200 of about 778,421 (286)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Heart Rate Responses During Official Kick Light Competition and Their Associations with Ventilatory Thresholds and VO₂max: An Exploratory Study. [PDF]

Sports (Basel)
Sousa-E-Silva P, Furtado G, Costa G, Martinho DV, Gomes R.   +4 more
europepmc   +1 more source

Double product break point estimates ventilatory threshold in individuals with type 2 diabetes. [PDF]

J Phys Ther Sci, 2016
Victor de Sousa C, Sales MM, Aguiar Sda S, Boullosa DA, Rosa Tdos S, Baldissera V, Simões HG.   +6 more
europepmc   +1 more source

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer, Mauro Contini, Michele Emdin, Damiano Magrì, Alice Bonomi, Elisabetta Salvioni, Fabrizio Celeste, Alberico Del Torto, Claudio Passino, Christophe D.J. Capelle, Chiara Arzilli, Emiliano Fiori, Nicolò Capra, Christina Kronberger, Nikita Ermolaev, Andreas Kammerlander, Beatrice Musumeci, Giuseppe Vergaro, Vincenzo Castiglione, René Rettl, Giacomo Tini, Andrea Baggiano, Iacopo Fabiani, Susanna Sciomer, Roza Badr Eslam, Piergiuseppe Agostoni   +25 more
wiley   +1 more source

Quantification of ventilatory control in sleep apnea: from physiological insight to computable loop gain. [PDF]

Sleep
Nassi T, Oppersma E, Donker DW, Westover MB, Thomas RJ.   +4 more
europepmc   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

The ventilatory response pattern to exercise across the age-span in healthy adults. [PDF]

Physiol Rep
Williams ZJ, Cenerini G, Schwendinger F, Knaier R, Wagner J, Hull JH, Schmidt-Trucksäss A.   +6 more
europepmc   +1 more source

MXene‐Induced Selective Ion Separation in Capacitive Deionization: Bridging Fundamentals With Frontier Innovations

Electron, EarlyView.
This review presents an in‐depth analysis of employing the MXenes electrodes in advancing ion‐selective capacitive deionization technologies, by exploring various strategies to achieve the desired selectivity. It highlights the critical challenges that hinder scalability and practical implementation. The review showcases the future opportunities toward
Rahat Alam, Linda Zou, Louis C. P. M. de Smet, Constantinos V. Chrysikopoulos   +3 more
wiley   +1 more source

The global scientific evolution of cardiopulmonary performance and threshold research in sports sciences during 2010-2025: a comparative bibliometric analysis based on web of science and scopus. [PDF]

Front Res Metr Anal
Soyal M, Aksoy Ö, Çelik NM, Özaǧır M, Gökmen ÜC, Caba U.   +5 more
europepmc   +1 more source