Results 41 to 50 of about 31,643 (255)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Perancangan UI/UX Aplikasi Social Media Venting untuk Remaja [PDF]
, 2021 Pencurahan emosi di media sosial atau kenal dengan istilah "social media venting" menjadi kebiasaan yang umum di temukan di media sosial Indonesia, terutama pada netizen berusia remaja.
Veda, Catherine
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Frontiers in PsychologyInterpersonal Emotion Regulation (IER) may serve as a critical link between the established roles of social support and emotion regulation in mitigating academic burnout. This study explored the hypothesis that IER influences academic burnout through its
Irene Messina +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Skylab venting propulsion [PDF]
, 1970 Skylab venting torque effects on attitude control ...
Smith, P. G.
core
Li-Ion Battery Fire Hazards and Safety Strategies
Energies, 2018 In the past five years, there have been numerous cases of Li-ion battery fires and explosions, resulting in property damage and bodily injuries. This paper discusses the thermal runaway mechanism and presents various thermal runaway mitigation approaches,
Lingxi Kong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Experimental studies of explosion venting in a cylindrical vessel
, 2002 Experiment investigations were carried out for the explosion venting in a 0.025m(3) vertical cylindrical vessel. Mixtures of 4.1% propane air were used with central bottom spark ignition.
Zawadzki A +5 more
core +1 more source