Results 91 to 100 of about 525,291 (388)
Frontiers in Neurology, 2015 Little is known regarding progressive enlargement of the ventricular system in symptomatic patients or asymptomatic subjects. Before eventual surgical treatment we evaluated the clinical and radiological features of an extremely rare group of patients ...
Paolo eMissori, Antonio eCurrà
doaj +1 more source
Chest, 2009 Pulmonary arterial hypertension (PAH) is a deadly disease in which vasoconstriction and vascular remodeling both lead to a progressive increase in pulmonary vascular resistance.
H. Bogaard +3 more
semanticscholar +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
Advanced Materials, EarlyView.We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin +17 more
wiley +1 more source
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source
β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation
Frontiers in Physiology, 2017 The transient outward K+ current, Ito, activates early in the cardiac myocyte action potential, to begin repolarization. Human Ito is generated primarily by two Kv4.3 potassium channel α subunit splice variants (Kv4.3L and Kv4.3S) that diverge only by a ...
Geoffrey W. Abbott
doaj +1 more source
Longitudinal analysis of fetal MRI in patients with prenatal spina bifida repair [PDF]
arXiv, 2019 Open spina bifida (SB) is one of the most common congenital defects and can lead to impaired brain development. Emerging fetal surgery methods have shown considerable success in the treatment of patients with this severe anomaly. Afterwards, alterations in the brain development of these fetuses have been observed.
arxiv
Comparison of shunt types in the Norwood procedure for single-ventricle lesions.
New England Journal of Medicine, 2010 BACKGROUND The Norwood procedure with a modified Blalock-Taussig (MBT) shunt, the first palliative stage for single-ventricle lesions with systemic outflow obstruction, is associated with high mortality.
R. Ohye +32 more
semanticscholar +1 more source
Advanced Materials Interfaces, EarlyView.Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu +6 more
wiley +1 more source
A two phase harmonic model for left ventricular function [PDF]
arXiv, 2006 A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude and the elastic constant of the oscillator are different. Taking into account the pressure within the left ventricle,
arxiv
Advanced Science, EarlyView.Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang +11 more
wiley +1 more source