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Considering the Risks and Costs of Solid Organ Xenotransplantation
Advanced Biology, Volume 9, Issue 4, April 2025.This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs +5 more
wiley +1 more source
β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation
Frontiers in Physiology, 2017 The transient outward K+ current, Ito, activates early in the cardiac myocyte action potential, to begin repolarization. Human Ito is generated primarily by two Kv4.3 potassium channel α subunit splice variants (Kv4.3L and Kv4.3S) that diverge only by a ...
Geoffrey W. Abbott
doaj +1 more source
A two phase harmonic model for left ventricular function [PDF]
arXiv, 2006 A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude and the elastic constant of the oscillator are different. Taking into account the pressure within the left ventricle,
arxiv
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Simulation of left ventricle fluid dynamics with mitral regurgitation from magnetic resonance images with fictitious elastic structure regularization [PDF]
arXiv, 2017 Computer modeling can provide quantitative insight into cardiac fluid dynamics phenomena that are not evident from standard imaging tools. We propose a new approach to modeling left ventricle fluid dynamics based on an image-driven model-based description of ventricular motion. In this approach, the end-diastolic geometry and time-dependent deformation
arxiv
Comparison of shunt types in the Norwood procedure for single-ventricle lesions.
New England Journal of Medicine, 2010 BACKGROUND The Norwood procedure with a modified Blalock-Taussig (MBT) shunt, the first palliative stage for single-ventricle lesions with systemic outflow obstruction, is associated with high mortality.
R. Ohye +32 more
semanticscholar +1 more source
Mechanical Metamaterials for Bioengineering: In Vitro, Wearable, and Implantable Applications
Advanced Engineering Materials, Volume 27, Issue 7, April 2025.Mechanical metamaterials with engineered architectures exhibit properties that differ from and greatly surpass those of their constituent bulk materials. This review summarizes the applications of mechanical metamaterials in bioengineering, focusing on advances in the last 5 years.
Madihah Kazim +2 more
wiley +1 more source
US Cardiology Review, 2020 Single-ventricle physiology occurs in patients with hypoplastic ventricular heart defects, either on the right or left, who have undergone stepwise palliation surgeries ending with the Fontan procedure.
Lydia Taranto, Tabitha Moe
doaj +1 more source
Pixel-wise Segmentation of Right Ventricle of Heart [PDF]
arXiv, 2019 One of the first steps in the diagnosis of most cardiac diseases, such as pulmonary hypertension, coronary heart disease is the segmentation of ventricles from cardiac magnetic resonance (MRI) images. Manual segmentation of the right ventricle requires diligence and time, while its automated segmentation is challenging due to shape variations and ...
arxiv
PROJECTILES IN THE CEREBRAL VENTRICLES [PDF]
The Journal of Nervous and Mental Disease, 1921 n ...
openaire +3 more sources