Advanced Science, EarlyView.A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni +6 more
wiley +1 more source
PathophysiologyThe use of catheter-based irreversible electroporation in clinical cardiac laboratories, termed pulsed-field ablation (PFA), is gaining international momentum among cardiac electrophysiology proceduralists for the non-thermal management of both atrial ...
Matthew Leonard Repp +1 more
doaj +1 more source
Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
Advanced Science, EarlyView.The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant [PDF]
, 2001 Anderson, RH +6 more
core +1 more source
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation
Advanced Science, EarlyView.LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao +9 more
wiley +1 more source
Emergency Resection of a Large Third Ventricle Colloid Cyst: Ipsilateral vs. Contralateral Interhemispheric Approach Based on the Hydrocephalus Status [PDF]
Wamedh E. Matti +4 more
openalex +1 more source
Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8
Advanced Science, EarlyView.Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong +11 more
wiley +1 more source
Development of the heart: (2) Septation of the atriums and ventricles [PDF]
, 2003 Robert H. Anderson
openalex +1 more source
Myocardial stress of the left ventricle during occupational vibration
, 2021 Sergei Tretyakov, А. А. Попова
openalex +1 more source
Associations between eGFR and albuminuria with right ventricular measures: the MESA-Right Ventricle study [PDF]
, 2023 Faeq Husain‐Syed +12 more
openalex +1 more source