Results 161 to 170 of about 576,684 (304)

Automatic segmentation of right ventricle on ultrasound images using sparse matrix transform and level set

, 2013
Xulei Qin, Zhibin Cong, Luma V. Halig, Baowei Fei   +3 more
openalex   +2 more sources

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

Advanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun, Seungju Yang, Jae Hyuk Kwon, Luiz Felipe Vecchietti, Ji Hyun Choi, Mi‐ra Choi, Keun Bon Ku, Hyun‐Joo Ro, Kyun‐Do Kim, Meeyoung Cha, Hyun Jung Chung, Ji Eun Oh, Ho Min Kim   +12 more
wiley   +1 more source

PM2.5 Induce Endothelial‐Mesenchymal Transition and Cardiac Fibrosis via the NCOA4‐Mediated Ferritinophagy

Advanced Science, EarlyView.
This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun, Mengyuan Wang, Lin Liu, Ruiyang Ding, Kanglin Yan, Shiqian Liu, Xiaoke Ren, Qing Xu, Zhiwei Sun, Qian Liu, Yi Yang, Junchao Duan   +11 more
wiley   +1 more source

Editorial: Women in Cardiac Electrophysiology: 2022

Frontiers in Physiology, 2023
Marianna Meo, Stefanie Fenske, Stefanie Fenske, Rasheda Chowdhury   +3 more
doaj   +1 more source

Criss cross heart: an outflow tract defect? [PDF]

Orphanet J Rare Dis
Bernheim S, Borgel A, Pingault V, Lyonnet S, Bonnet D, Meilhac SM, Houyel L.   +6 more
europepmc   +1 more source

An unexpected spherical mass in the left ventricle accidentally found during abdominal ultrasound [PDF]

, 2018
Katarzyna Kurnicka, Krzysztof Jankowski, Olga Zdończyk, Piotr Pruszczyk   +3 more
openalex   +1 more source

Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation

Advanced Science, EarlyView.
A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu, Hongtao Song, Limin He, Zhihao Hu, Yu Li, Chao Xu, Shaojie Liu, Jun Jiang, Yike Zhou, Zhengxuan Li, Zeyu Li, Keying Zhang, Shuaijun Ma, Ruochen Qi, Shichao Han, Changhong Shi, Weihong Wen, Donghui Han, Weijun Qin   +18 more
wiley   +1 more source

Double inlet left ventricle in a 12-year-old European bison: a case report with anatomical assessment and postmortem computed tomography evaluation. [PDF]

BMC Vet Res
Godlewska A, Barszcz K, Przespolewska H, Bielecki W, Zabiega K, Buczyński M, Mądry W, Szymczak K, Kwiatkowska M, Grzegorczyk M, Szaluś-Jordanow O.   +10 more
europepmc   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

The stroke that unveiled a silent threat: rupture and thrombosis of hydatid cyst in the left ventricle- a case report. [PDF]

J Cardiothorac Surg
Es-Saad O, Abetti A, Belghit H, Darraz A, Alkouh R, Labib S.   +5 more
europepmc   +1 more source