Results 201 to 210 of about 546,461 (357)

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Large dissecting sinus of Valsalva aneurysm creating a 'triple ventricle' appearance: case report. [PDF]

Eur Heart J Case Rep
Kumar SS, Mondal S, Radhakrishnan J, Das R.   +3 more
europepmc   +1 more source

Laryngeal polypus growing on a prolapsed ventricle of morgagni [PDF]

, 1901
S. Monselles
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain

Advanced Electronic Materials, EarlyView.
In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim, Sehwan Park, Haeyun Lee, Jimin Lee, Namsun Chou, Hyogeun Shin   +5 more
wiley   +1 more source

Triple sheath neuroendoscopic combination technique for managing complete intraventricular hemorrhage casting in patients with cerebral hemorrhage. [PDF]

Front Neurol
Shafiq Z, Zhou L, Jiang X, Li Z, Song P, Zhang S, Cai Q.   +6 more
europepmc   +1 more source

A CASE OF ANEURYSM OF THE LEFT VENTRICLE. [PDF]

, 1898
Ernest B. Sangree
openalex   +1 more source

Knowledge, Attitude, and Practice on Atrial Fibrillation and Atrial Fibrillation Screening in High‐Risk Population: A Cross‐Sectional Study

AGING MEDICINE, EarlyView.
Distribution of KAP scores for participants ≤ 65 versus > 65 years. ABSTRACT Objectives Atrial fibrillation (AF) is a common clinical arrhythmia. Failure to identify AF leaves patients at a considerably higher risk of disability and death, making its early screening and prevention extremely important. This study aimed to investigate knowledge, attitude,
Zhong Yi, Xinxin Yan, Shaozhi Xi, Lijuan Zhu, Rui Liu, Jing Li, Songwei Ru, Xiu Zheng, Jingxuan Qiu, Chunqi Wang, Na Guo, Yimin Wang, Dayong Gao   +12 more
wiley   +1 more source

An isolated double-inlet right ventricular malformation: a case report and review of the literature. [PDF]

J Med Case Rep
Borghol W, Alfaksh F, Karaja S, Barakat L, Takkem S.   +4 more
europepmc   +1 more source