Results 291 to 300 of about 778,572 (398)

Curved Bistable Origami‐Inspired Flexible Transcatheter Mitral Valve Clamping

open access: yesAdvanced Science, EarlyView.
A lightweight bistable curved origami dilator combines reversible deformation and high stability, offering a promising solution for minimally invasive mitral valve repair. Abstract Curved origami exhibits remarkable potential for minimally invasive medical applications owing to its unique geometric programmability and mechanical tunability. Building on
Siyu Gao   +4 more
wiley   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

open access: yesAdvanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong   +22 more
wiley   +1 more source

Challenging diagnosis of a coronary arteriovenous malformation: a case report. [PDF]

open access: yesGen Thorac Cardiovasc Surg Cases
Imaizumi Y   +7 more
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

open access: yesAdvanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang   +27 more
wiley   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

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