Results 51 to 60 of about 546,461 (357)

Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury

Journal of Neuroinflammation, 2011
Background The combination of diffuse brain injury with a hypoxic insult is associated with poor outcomes in patients with traumatic brain injury. In this study, we investigated the impact of post-traumatic hypoxia in amplifying secondary brain damage ...
Bellander Bo-Michael, Hellewell Sarah C, Yan Edwin B, Agyapomaa Doreen A, Morganti-Kossmann M Cristina   +4 more
doaj   +1 more source

Identifying molecular and functional similarities and differences between human primary cardiac valve interstitial cells and ventricular fibroblasts

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Fibroblasts are mesenchymal cells that predominantly produce and maintain the extracellular matrix (ECM) and are critical mediators of injury response.
Martha E. Floy, Fathima Shabnam, Sophie E. Givens, Vaidehi A. Patil, Yunfeng Ding, Grace Li, Sushmita Roy, Amish N. Raval, Amish N. Raval, Eric G. Schmuck, Kristyn S. Masters, Brenda M. Ogle, Brenda M. Ogle, Sean P. Palecek   +13 more
doaj   +1 more source

A univentricular heart : tricuspid atresia [PDF]

, 2013
A two-year-three-month-old boy was diagnosed with tricuspid atresia. This condition requires three surgical interventions, of which he has already had two. He has now presented to hospital with shortness of breath.
Mifsud, Simon, Schembri, Emma
core  

SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher, Dominika Stastna, Ingrid Menkyova, Vaclav Capek, Jiri Lindner, Petra Nytrova, Jan Krasensky, Eliza Varju, Miguel D'haeseleer, Eva Kubala Havrdova, Dana Horakova, Manuela Vaneckova, Niels Bergsland   +12 more
wiley   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

The Development of Compartmentation of cAMP Signaling in Cardiomyocytes: The Role of T-Tubules and Caveolae Microdomains

Journal of Cardiovascular Development and Disease, 2018
3′-5′-cyclic adenosine monophosphate (cAMP) is a signaling messenger produced in response to the stimulation of cellular receptors, and has a myriad of functional applications depending on the cell type.
Navneet K. Bhogal, Alveera Hasan, Julia Gorelik   +2 more
doaj   +1 more source

Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2016
Objectives This study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-tochoroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined ...
Aderemi Ishola, Christianah Mopelola Asaleye, Oluwagbemiga Oluwole Ayoola, Olabisi Morebise Loto, Bukunmi Michael Idowu   +4 more
doaj   +2 more sources

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Detecção precoce da disfunção diastólica global e regional do ventrículo esquerdo no lúpus eritematoso sistêmico: o papel da ecocardiografia Early detection of global and regional left ventricular diastolic dysfunction in systemic lupus erythematosus: the role of the echocardiography

Revista Brasileira de Reumatologia, 2010
INTRODUÇÃO: A ecocardiografia bidimensional é um método de diagnóstico por imagem não invasivo que avalia, de modo eficaz, a função diastólica global e regional do ventrículo esquerdo.
Ana Claudia Soares Teixeira, Eloisa Bonfá, Nathan Herskowictz, Alfonso Júlio Guedes Barbato, Eduardo Ferreira Borba   +4 more
doaj   +1 more source

Pathways Regulating Establishment and Maintenance of Cardiac Chamber Identity in Zebrafish

Journal of Cardiovascular Development and Disease, 2021
The vertebrate heart is comprised of two types of chambers—ventricles and atria—that have unique morphological and physiological properties. Effective cardiac function depends upon the distinct characteristics of ventricular and atrial cardiomyocytes ...
Yao Yao, Amanda N. Marra, Deborah Yelon
doaj   +1 more source