Results 51 to 60 of about 586,384 (350)

Functional role of t-tubules on calcium transients in canine cardiac myocytes

Heart and Mind, 2019
Background: A loss of t-tubules and alterations in ultrastructure occur in cultured ventricular myocytes. A similar alteration in t-tubules and ultrastructure is well documented under certain pathological conditions such as heart failure. We examined the
Alicia A Barnes, Zachary E Williams, Samuel Olzcyk, Alida Cooke, Jonathan A Cordeiro, Tanya Zeina, Rueben Mathew, Jacqueline A Treat, Gary L Aistrup, Jonathan M Cordeiro   +9 more
doaj   +1 more source

Pro-Arrhythmic Effects of Discontinuous Conduction at the Purkinje Fiber-Ventricle Junction Arising From Heart Failure-Induced Ionic Remodeling – Insights From Computational Modelling

Frontiers in Physiology, 2022
Heart failure is associated with electrical remodeling of the electrical properties and kinetics of the ion channels and transporters that are responsible for cardiac action potentials.
Kun Jian, Chen Li, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang   +5 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Early Left Ventricular Involvement Detected by Cardiovascular Magnetic Resonance Feature Tracking in Arrhythmogenic Right Ventricular Cardiomyopathy: The Effects of Left Ventricular Late Gadolinium Enhancement and Right Ventricular Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Left ventricular (LV) involvement is common in arrhythmogenic right ventricular cardiomyopathy (ARVC). We aim to evaluate LV involvement in ARVC patients by cardiovascular magnetic resonance feature tracking.
Xiuyu Chen, Lu Li, Huaibin Cheng, Yanyan Song, Keshan Ji, Lin Chen, Tongtong Han, Minjie Lu, Shihua Zhao   +8 more
doaj   +1 more source

Efficacy of Whole-Ventricular Radiotherapy in Patients Undergoing Maximal Tumor Resection for Glioblastomas Involving the Ventricle

Frontiers in Oncology, 2021
Background and PurposePatients with glioblastoma (GBM) involving the ventricles are at high risk of ventricle opening during surgery and potential ventricular tumor spread.
Kyung Hwan Kim, Jihwan Yoo, Nalee Kim, Ju Hyung Moon, Hwa Kyung Byun, Seok-Gu Kang, Jong Hee Chang, Hong In Yoon, Chang-Ok Suh, Chang-Ok Suh   +9 more
doaj   +1 more source

Adipokines and the Right Ventricle: The MESA-RV Study. [PDF]

, 2015
ObjectiveObesity is associated with changes in both right (RV) and left (LV) ventricular morphology, but the biological basis of this finding is not well established. We examined whether adipokine levels were associated with RV morphology and function in
Bluemke, David A, Criqui, Michael H, Harhay, Michael O, Kawut, Steven M, Kizer, Jorge R, Lima, João AC, Tracy, Russell   +6 more
core   +3 more sources

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

A coupled mitral valve -- left ventricle model with fluid-structure interaction

, 2017
Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX, Ch'ng, Quee-Lim, Currie, Michael, Grundy, Laura J, Hokanson, Jim, Javer, Avelino, Kerr, Rex, Lee, Chee Wai, Li, Chris, Li, Kezhi, Schafer, William R, Yemini, Eviatar   +11 more
core   +3 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Application of NASTRAN for stress analysis of left ventricle of the heart [PDF]

, 1975
Knowing the stress and strain distributions in the left ventricular wall of the heart is a prerequisite for the determination of the muscle elasticity and contractility in the process of assessing the functional status of the heart.
Pao, Y. C., Ritman, E. L., Wang, H. C.
core   +1 more source