Results 101 to 110 of about 970,341 (351)

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Difficult management of a patient presenting with recurrent syncope caused by diffuse vasospasm

İstanbul Kuzey Klinikleri, 2018
Spontaneous and simultaneous multivessel coronary artery spasm may present with multisite myocardial ischemia, atrioventricular block, acute lung edema, cardiogenic shock, or ventricular fibrillation.
Abdulkadir Uslu, Serdar Demir, Munevver Sari, Cem Dogan, Ozge Akgun, Mehmet Celik, Taylan Akgun   +6 more
doaj   +1 more source

Electrocardiographic and Skin Manifestations of Turner Syndrome: Association With Cardiovascular Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital heart disease (CHD) and dermatologic conditions such as lymphedema and acquired melanocytic nevi (AMN) are common in Turner Syndrome (TS). We hypothesized that abnormalities of cranial neural crest cell derivatives drive the skin and heart manifestations of TS. We conducted joint cardiac and skin examinations of volunteers at a 2023
Sarah Elsaim, Brett Vernier, Van Thi Thanh Truong, Riya T. Patel, Matthew Brown, Martin Chacon Portillo, Megan Rogge, David Rodriguez‐Buritica, Siddharth K. Prakash   +8 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Ventricular arrhythmia during automated lead testing: What is the mechanism?

Indian Pacing and Electrophysiology Journal, 2022
Sahra Jama, Benedict M. Wiles, Magdi M. Saba, Michael C. Waight, Anthony C. Li   +4 more
doaj   +1 more source

Myocardial Function, Heart Failure and Arrhythmia in Marfan Syndrome: A Systematic Literature Review

Diagnostics, 2020
Marfan syndrome (MFS) is a heritable systemic connective tissue disease with important cardiovascular involvement, including aortic root dilatation and mitral valve prolapse.
Anthony Demolder, Yskert von Kodolitsch, Laura Muiño-Mosquera, Julie De Backer   +3 more
doaj   +1 more source

Regulation of gap junction function; the role of nitric oxide. [PDF]

, 2013
Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Kovács Mária, Miskolczi Gottfried, Végh, Ágnes, Gönczi, Márton, Végh Ágnes, Gottfried Miskolczi, Miskolczi eGottfried, Miskolczi, Gottfried, Kovács, Mária, Gönczi eMárton, Kovács eMária, Gönczi Márton, Ágnes Végh, Mária Kovács, Ágnes eVégh, Márton Gönczi   +15 more
core   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Dyssynchrony and the Risk of Ventricular Arrhythmias

JACC: Cardiovascular Imaging, 2013
The aim of our study was to evaluate the relationship between left ventricular (LV) dyssynchrony and the risk of ventricular tachycardia (VT) or ventricular fibrillation (VF) in patients enrolled in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy) trial.Intraventricular mechanical dyssynchrony ...
Kutyifa, Valentina, Pouleur, Anne-Catherine, Knappe, Dorit, Al-Ahmad, Amin, Gibinski, Michal, Wang, Paul J., McNitt, Scott, Merkely, Bela, Goldenberg, Ilan, Solomon, Scott D., Moss, Arthur J., Zareba, Wojciech   +11 more
openaire   +3 more sources

Modelagem matemática e avaliação de novos parâmetros para estudo do efeito de fármacos na repolarização ventricular em indivíduos com diabetes [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2012.Esta pesquisa apresenta uma metodologia completa para a modelagem matemática de sinais de ...
Charry, Oscar Julián Perdomo
core