Results 31 to 40 of about 104,795 (251)

Direct Gravity‐Induced Modulation of Cardiac Conduction Pathways Evidenced Through Propagation Features in Electrophysiological Mapping

Advanced Materials Technologies, EarlyView.
A high‐density wearable body‐surface potential mapping array reveals how gravity reshapes cardiac conduction in real time. By resolving spatiotemporal delay patterns invisible to conventional ECG, the platform uncovers posture‐dependent electrophysiological adaptations across the thorax.
Ruben Ruiz‐Mateos Serrano, Matias L. Picchio, Daniele Mantione, David Mecerreyes, George G. Malliaras   +4 more
wiley   +1 more source

Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease

JACC: Case Reports, 2019
A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I.
Stefano Figliozzi, MD, Stefania Rizzo, MD, Chun-Yan Cheng, MD, PhD, Sabino Iliceto, MD, Cristina Basso, MD, PhD, Alida L.P. Caforio, MD, PhD, Renzo Marcolongo, MD   +6 more
doaj   +1 more source

Anti‐Inflammatory and Antiarrhythmic Effects of Beta Blocker in a Rat Model of Rheumatoid Arthritis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Patients with rheumatoid arthritis are at twice the risk of ventricular arrhythmia and sudden cardiac death as the general population. We hypothesize that β‐blocker treatment of rheumatoid arthritis is antiarrhythmic by producing synergistic ...
Ting‐Tse Lin, Yen‐Ling Sung, Jhen‐Yang Syu, Kia‐Yuan Lin, Hung‐Jui Hsu, Min‐Tsun Liao, Yen‐Bin Liu, Shien‐Fong Lin   +7 more
doaj   +1 more source

Ventricular tachycardia and pregnancy

International Journal of Cardiology Congenital Heart Disease, 2021
The risk of developing new-onset arrhythmia or exacerbation of a pre-existing arrhythmia is increased during pregnancy because of profound physiological and hormonal changes.
Nicole Schenkelaars, Robert M. Kauling, Karishma P. Ramlakhan, Sing-Chien Yap, Jérôme M.J. Cornette, Jolien W. Roos-Hesselink   +5 more
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

The effect of revascularization on mortality and risk of ventricular arrhythmia in patients with ischemic cardiomyopathy

BMC Cardiovascular Disorders, 2020
Background There is clear evidence that patients with prior myocardial infarction and a reduced ejection fraction benefit from implantation of a cardioverter-defibrillator (ICD).
Ahmad Alkharaza, Mousa Al-Harbi, Ihab El-sokkari, Steve Doucette, Ciorsti MacIntyre, Christopher Gray, Amir Abdelwahab, John L. Sapp, Martin Gardner, Ratika Parkash   +9 more
doaj   +1 more source

Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia

Scientific Reports, 2021
Premature ventricular contraction (PVC), a common arrhythmia affecting 1–2% of the general population, has been considered to have a benign clinical course.
Yun Gi Kim, Yun Young Choi, Kyung-Do Han, Kyoung Jin Min, Ha Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim   +7 more
doaj   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source