Results 31 to 40 of about 108,740 (262)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Anti‐Inflammatory and Antiarrhythmic Effects of Beta Blocker in a Rat Model of Rheumatoid Arthritis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Patients with rheumatoid arthritis are at twice the risk of ventricular arrhythmia and sudden cardiac death as the general population. We hypothesize that β‐blocker treatment of rheumatoid arthritis is antiarrhythmic by producing synergistic ...
Ting‐Tse Lin, Yen‐Ling Sung, Jhen‐Yang Syu, Kia‐Yuan Lin, Hung‐Jui Hsu, Min‐Tsun Liao, Yen‐Bin Liu, Shien‐Fong Lin   +7 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Ventricular tachycardia and pregnancy

International Journal of Cardiology Congenital Heart Disease, 2021
The risk of developing new-onset arrhythmia or exacerbation of a pre-existing arrhythmia is increased during pregnancy because of profound physiological and hormonal changes.
Nicole Schenkelaars, Robert M. Kauling, Karishma P. Ramlakhan, Sing-Chien Yap, Jérôme M.J. Cornette, Jolien W. Roos-Hesselink   +5 more
doaj   +1 more source

Anger and ventricular arrhythmias [PDF]

Current Opinion in Cardiology, 2010
Although anecdotal evidence has long suggested links between emotion and ventricular arrhythmia, more recent studies have prospectively demonstrated the arrhythmogenic effects of anger, as well as mechanisms underlying these effects.Epidemiological studies reveal that psychological stress increases sudden death, as well as arrhythmias, in patients with
openaire   +2 more sources

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease

JACC: Case Reports, 2019
A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I.
Stefano Figliozzi, MD, Stefania Rizzo, MD, Chun-Yan Cheng, MD, PhD, Sabino Iliceto, MD, Cristina Basso, MD, PhD, Alida L.P. Caforio, MD, PhD, Renzo Marcolongo, MD   +6 more
doaj   +1 more source

The effect of revascularization on mortality and risk of ventricular arrhythmia in patients with ischemic cardiomyopathy

BMC Cardiovascular Disorders, 2020
Background There is clear evidence that patients with prior myocardial infarction and a reduced ejection fraction benefit from implantation of a cardioverter-defibrillator (ICD).
Ahmad Alkharaza, Mousa Al-Harbi, Ihab El-sokkari, Steve Doucette, Ciorsti MacIntyre, Christopher Gray, Amir Abdelwahab, John L. Sapp, Martin Gardner, Ratika Parkash   +9 more
doaj   +1 more source

Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia

Scientific Reports, 2021
Premature ventricular contraction (PVC), a common arrhythmia affecting 1–2% of the general population, has been considered to have a benign clinical course.
Yun Gi Kim, Yun Young Choi, Kyung-Do Han, Kyoung Jin Min, Ha Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim   +7 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source