Results 61 to 70 of about 165,166 (258)

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Double Ventricular Responses Leading to Reversible Cardiomyopathy as Late Complication after Slow-Pathway Ablation

Case Reports in Cardiology, 2015
Double ventricular response is a rare arrhythmia that results from simultaneous antegrade conduction over the fast and slow pathways of AV node. Double ventricular responses may lead to arrhythmia-related cardiomyopathy.
Umut Celikyurt, Meinrad Gawaz, Juergen Schreieck, Peter Seizer   +3 more
doaj   +1 more source

Accuracy of prediction of infarct-related arrhythmic circuits from image-based models reconstructed from low and high resolution MRI. [PDF]

, 2015
Identification of optimal ablation sites in hearts with infarct-related ventricular tachycardia (VT) remains difficult to achieve with the current catheter-based mapping techniques.
Arevalo, Hermenegild, Ashikaga, Hiroshi, Deng, Dongdong, Halperin, Henry, McVeigh, Elliot, Pashakhanloo, Farhad, Prakosa, Adityo, Trayanova, Natalia   +7 more
core   +2 more sources

Ventricular divergence correlates with epicardial wavebreaks and predicts ventricular arrhythmia in isolated rabbit hearts during therapeutic hypothermia [PDF]

, 2020
INTRODUCTION: High beat-to-beat morphological variation (divergence) on the ventricular electrogram during programmed ventricular stimulation (PVS) is associated with increased risk of ventricular fibrillation (VF), with unclear mechanisms.
Chen, Shih-Ann, Haugan, Ketil, Hsieh, Wan-Hsin, Hsieh, Yu-Cheng, Huang, Jin-Long, Larsen, Bjarne D., Li, Cheng-Hung, Liao, Ying-Chieh, Lin, Jiunn-Cherng, Lin, Shien-Fong, Lin, Wei-Wen, Lin, Yenn-Jiang, Lo, Men-Tzung, Tuan, Ta-Chuan, Weng, Chi-Jen, Wu, Tsu-Juey, Yeh, Hung-I   +16 more
core   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Resistant Ventricular Arrhythmia and the Role of Overdrive Pacing in the Suppression of the Electrical Storm

Case Reports in Cardiology, 2019
Ventricular arrhythmia storm is a state of cardiac instability characterized by multiple ventricular arrhythmias or multiple ICD therapies within a 24-hour duration.
Mohamed Magdi, Mahmood Mubasher, Hakam Alzaeem, Tahir Hamid   +3 more
doaj   +1 more source

Pacinian Corpuscle‐Inspired Strain Conversion Enables Ultrasensitive, Linear, and Broad‐Range Piezoelectric Sensing for Cardiovascular Health Monitoring

Advanced Science, EarlyView.
A bioinspired piezoelectric sensor mimicking Pacinian corpuscles is developed to enable ultrasensitive and linear pressure sensing. A multilayer grooved architecture converts normal pressure into in‐plane strain, delivering high sensitivity, wide linear range, and efficient energy harvesting, enabling high‐fidelity wrist pulse monitoring and ...
Qi Yang, Zhongqian Song, Shengjie Liu, Yingming Ma, Weiyan Li, Huijun Kong, Cuiyu Liu, Yu Bao, Li Niu   +8 more
wiley   +1 more source

Pacemaker Prevention Therapy in Drug–refractory Paroxysmal Atrial Fibrillation: Reliability of Diagnostics and Effectiveness of Prevention Pacing Therapy in Vitatron™ Selection® device [PDF]

, 2006
Introduction. Atrial fibrillation (AF), the most common and rising disorder of cardiac rhythm, is quite difficult to control and/or to treat. Non pharmacological therapies for AF may involve the use of dedicated pacing algorithms to detect and prevent ...
Dell’Orto, Simonetta, Greco, Enrico Maria, Terranova, Paolo, Terranova, Peppino, Valli, Paolo   +4 more
core   +2 more sources

Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]

, 2016
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M, Field, Michael E, Hayes, Kevin, Hoffmayer, Kurt S, Scheinman, Melvin M   +4 more
core   +2 more sources

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

Advanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng, Niels Harlaar, Juan Zhang, Sven O. Dekker, Nina N. Kudryashova, Huiling Zhou, Cindy I. Bart, TianYi Jin, Georgy Derevyanko, Willem van Driel, Alexander V. Panfilov, René H. Poelma, Antoine A. F. de Vries, GuoQi Zhang, Tim De Coster, Daniël A. Pijnappels   +15 more
wiley   +1 more source