Results 211 to 220 of about 192,727 (304)

Reappraising Use of Flecainide for Atrial Fibrillation and Ventricular Arrhythmias in Structural Heart Disease Patients. [PDF]

Medicina (Kaunas)
Tsiachris D, Kotoulas SC, Doundoulakis I, Antoniou CK, Botis M, Pamporis K, Argyriou N, Karanikola AE, Tsioufis P, Kordalis A, Tsioufis K.   +10 more
europepmc   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Long-term outcome of catheter ablation of left fascicular ventricular arrhythmias. [PDF]

J Interv Card Electrophysiol
My I, Moser F, Loeck FW, Obergassel J, Rottner L, Lemoine MD, Kirchhof P, Steven D, Sultan A, Willems S, Meyer C, Reissmann B, Rillig A, Metzner A, Ouyang F.   +14 more
europepmc   +1 more source

Cardiac resynchronization therapy and pulmonary artery banding in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block

Pediatric Investigation, EarlyView.
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng, Fan Yang, Quanlin Li, Kai Ma, Zheng Dou, Kunjing Pang, Xinjie Lin, Shoujun Li, Xu Wang   +8 more
wiley   +1 more source

Stellate ganglion modulation: An old therapy with a new twist for treatment of ventricular arrhythmias. [PDF]

Indian Pacing Electrophysiol J
Avasthi S, Vaseghi M.
europepmc   +1 more source

Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement: A meta‐analysis

Precision Medical Sciences, EarlyView.
Central illustration: Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement. Abstract Bicuspid aortic valve (BAV) is a common congenital anomaly leading to early aortic stenosis.
Muhammad Huzaifa Ahmed Khan, Muneeb Khawar, Asad Ullah Farooq, Azooba Khalid, Syed Muhammad Ahsan, M. Hamza Naseer Awan, Muhammad Soban Nisar, Asim Elahi, Muhammad Aqib Faizan, Iqra Shahid, Abdullah Munir Ahmed, Faseeh Haider, Rejina Chhetri   +12 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Effect of scar distribution on transmural and planar repolarization gradients and dispersion in non-ischemic cardiomyopathies with ventricular arrhythmias. [PDF]

Europace
Tonko JB, Cabrera-Borrego E, Sánchez-Millán P, Jiménez-Jáimez J, Chow A, Lambiase PD.   +5 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Family history of sudden cardiac death as a risk marker for ventricular arrhythmias in laminopathies. [PDF]

Europace
Giordano G, Proukhnitzky J, Fer F, Bloch A, Thuillot M, Maupain C, Magnin-Poull I, Jonveaux I, Palmyre A, Bertinotti A, Mansencal N, de Chillou C, Richard P, Gandjbakhch E, Charron P.   +14 more
europepmc   +1 more source