Results 251 to 260 of about 1,029,845 (331)

Pulsed field ablation for ventricular arrhythmias: From mechanistic foundations to clinical translation. [PDF]

Heart Rhythm O2
Li H, Zhang H, Tian M, Yang S, Zhao X, Liao Q, Li S, Yang D, Guo F.   +8 more
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Ventricular Arrhythmias and Myocardial Infarction: Electrophysiological and Neuroimmune Mechanisms. [PDF]

Biomedicines
Zheng M, Zhou Z, Deng KQ, Zhang H, Zeng Z, Zhang Y, He B, Cai H, Lu Z.   +8 more
europepmc   +1 more source

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, EarlyView.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source

Idiopathic Annular Ventricular Arrhythmias. [PDF]

Arrhythm Electrophysiol Rev
Yoneda ZT, Stevenson WG.
europepmc   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source

Clinical phenotypes across age groups and the predictive value of NT-proBNP for ventricular arrhythmias in left ventricular non-compaction: a multicenter cohort study. [PDF]

J Transl Med
Jiang J, Zhang X, Yang K, Kong D, Qin X, Sun Y, Xiao Y, Gu Y, Zhang B, Ma M, Tian T, Hu A.   +11 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Systolic Dyssynchrony Index in Hypertrophic Cardiomyopathy: Association With Ventricular Arrhythmias and Risk Prediction. [PDF]

JACC Asia
Wang R, Zhuang H, Xu N, Zhang L, Xing J, Zhang T, Kang L, Song L, Pang K.   +8 more
europepmc   +1 more source