Results 91 to 100 of about 195,940 (363)

Hemolysis in a continuous-flow ventricular assist device with/without chamfer

Advances in Mechanical Engineering, 2017
Ventricular assist device has been increasingly used in the treatment of end-stage heart failure, with a high incidence of hemolysis in clinical use, which is a serious problem to be solved.
Donghai Li, Qingyu Wu, Jingjing Ji, Shuhong Liu, Mingkui Zhang, Yu Zhang   +5 more
doaj   +1 more source

Blood Damage in Ventricular Assist Devices [PDF]

The International Journal of Artificial Organs, 2016
Advancements in both the design of mechanical circulatory support (MCS) and medical care for recipients have led to steady improvements in patient survival over the last decades. Indeed, current generations of ventricular assist devices (VADs), for example, provide important therapeutic alternatives for individuals with heart failure that may be ...
Simmonds, M, Thamsen, B, Kertzscher, U
openaire   +6 more sources

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Stochastic Modelling and Dynamic Analysis of Cardiovascular System with Rotary Left Ventricular Assist Devices [PDF]

Mathematical Problems in Engineering, 2018, 2018
The left ventricular assist device (LVAD) has been used for end-stage heart failure patients as a therapeutic option. The aortic valve plays a critical role in heart failure and its treatment with LVAD. The cardiovascular-LVAD model is often used to investigate the physiological demands required by patients and predict the hemodynamic of the native ...
arxiv  

Left ventricular assist device (LVAD) enables survival during 7 h of sustained ventricular fibrillation [PDF]

, 2017
We describe the case of a patient implanted with a DeBakey left ventricular assist device (LVAD) as bridge to transplant who survived 7 h of ventricular fibrillation.
Lachat, Mario L., Salzberg, Sacha P., Turina, Marko I., Zünd, Gregor   +3 more
core  

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Cutting the Cord: A Case of Late Presenting Driveline Infection [PDF]

, 2020
Ventricular assist device (VAD) related infection, specifically driveline infection, is a common complication after VAD implantation. A 45-year old patient with a delayed skin infection at the site of the original driveline nearly one year after VAD ...
Eyadiel, Lauren, Laughey, Brian, Pisani, Barbara   +2 more
core   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

Eulerian Formulation of the Tensor-Based Morphology Equations for Strain-Based Blood Damage Modeling [PDF]

Computer Methods in Applied Mechanics and Engineering, Volume 426, 2024, 116979
The development of blood-handling medical devices, such as ventricular assist devices, requires the analysis of their biocompatibility. Among other aspects, this includes hemolysis, i.e., red blood cell damage. For this purpose, computational fluid dynamics (CFD) methods are employed to predict blood flow in prototypes.
arxiv   +1 more source