Results 91 to 100 of about 67,462 (301)

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

Advanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui, Neela K. Codadu, Daman Rathore, Guanghui Li, Marcello Meneghetti, Anders L. Bøcker, Rune W. Berg, Rob C. Wykes, Christos Markos   +8 more
wiley   +1 more source

Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: A case report [PDF]

, 2017
Lung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem, many programs have begun to use donors with extended criteria (marginal donors).
Calabrese, Fiorella, Calabrese, Francesca, DI GREGORIO, Guido, Loy, Monica, Marulli, Giuseppe, Rea, Federico, Rebusso, Alessandro, Schiavon, Marco   +7 more
core   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Simulation of dilated heart failure with continuous flow circulatory support [PDF]

, 2014
Lumped parameter models have been employed for decades to simulate important hemodynamic couplings between a left ventricular assist device (LVAD) and the native circulation.
A Ferreira, AG Rose, AM Katz, Antonio Ferreira, B Zaret, Bradley Keller, D Burkhoff, D Chung, D Morley, DA Kass, DJ Farrar, F Moscato, G Kovacs, H Schima, H Suga, I Nordenfelt, J Gorcsan III, J Ross, James Antaki, JC Matthews, John Gorcsan, JR Fitzpatrick III, JR Fitzpatrick III, KW Gwak, KW Gwak, LA Soloff, LW Stevenson, M Kinoshita, M Palardy, M Ursino, M Vollkron, MA Simon, MS Slaughter, Natasha Loghmanpour, NC Dang, O Lisy, PK Nair, RE Ehrsam, RL Kormos, RL Kormos, S Maybaum, S Nakatani, S Vandenberghe, SG Shroff, SJ Sarnoff, Stijn Vandenberghe, U Thadani, Vincenzo Lionetti, W Little, Y Shi, Yajuan Wang   +50 more
core   +4 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

LVAD pannus complicating destination therapy

Human Pathology: Case Reports, 2017
Despite advances in technology, ventricular assist devices still experience a number of complications limiting their long-term use. We present a 73-year-old woman implanted with a left ventricular assist device (LVAD) five years prior due to end-stage ...
Maya Ignaszewski, Margaret Robin B. Cases, Davide Salina, Elizabeth Swiggum, Anson Cheung, Andrew P. Ignaszewski, Michael A. Seidman   +6 more
doaj   +1 more source

Clinical trial of FK 506 immunosuppression in adult cardiac transplantation [PDF]

, 1992
The new immunosuppressive agent FK 506 was used as primary immunotherapy in conjunction with low-dose steroids and azathioprine in 72 patients subsequent to orthotopic cardiac transplantation.
Armitage, Bartley P. Griffith, Billingham, Dew, Fung, Gary C. Marrone, John Fung, John M. Armitage, Kormos, Kusne, Robert L. Hardesty, Robert L. Kormos, Shigeki Morita, Starzl, Starzl, Tamura, Thomas E. Starzl, Todo   +17 more
core   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

Advanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng, Niels Harlaar, Juan Zhang, Sven O. Dekker, Nina N. Kudryashova, Huiling Zhou, Cindy I. Bart, TianYi Jin, Georgy Derevyanko, Willem van Driel, Alexander V. Panfilov, René H. Poelma, Antoine A. F. de Vries, GuoQi Zhang, Tim De Coster, Daniël A. Pijnappels   +15 more
wiley   +1 more source

Passive control of a bi-ventricular assist device : an experimental and numerical investigation [PDF]

, 2008
For the last two decades heart disease has been the highest single cause of death for the human population. With an alarming number of patients requiring heart transplant, and donations not able to satisfy the demand, treatment looks to mechanical ...
Gaddum, Nicholas Richard
core   +1 more source

Water‐Assisted Exfoliation of HfO2‐Based Membrane for Flexible Robust Ferroelectric Synaptic Transistors

Advanced Science, EarlyView.
A flexible freestanding HfO2‐based ferroelectric membrane is achieved via a water‐assisted exfoliation technique using a Sr4Al2O₇ sacrificial layer. The BaTiO3/Hf0.5Zr0.5O2/BaTiO3 heterostructure maintains robust ferroelectricity and exhibits reliable synaptic plasticity.
Han Zhang, Miao Zeng, Jingxin Chen, Lei Wang, Sai Jiang, Qian Cao, Xuebo Li, Zekun Hou, Chun Shen, Yulin Gan, Ning Fang, Zhaoliang Liao, Ziyao Zhou, Lin Hao   +13 more
wiley   +1 more source