Results 111 to 120 of about 67,462 (301)

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes   +3 more
wiley   +1 more source

Wireless blood pressure sensor implantation in sheep: A detailed technique

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer   +10 more
wiley   +1 more source

Implementing a Programmatic Approach to Identify and Promote Ventricular Recovery in Pediatric Patients Supported With Ventricular Assist Devices

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In October 2022, our center implemented a standardized program to promote ventricular recovery in pediatric patients supported with durable ventricular assist devices. We report our experience and outcomes. Methods The initiative consists of 4
Catherine M. Montgomery   +18 more
doaj   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu   +5 more
wiley   +1 more source

Computer simulation of platelet activation in a pulsatile ventricular assist device, through finite elements and a simplified geometry [PDF]

open access: yes, 2017
Ventricular assist devices are a technological solution for patients who suffer from cardiac insufficiency and await a transplant. In this work, a new design of an implantable pulsatile blood pump is analyzed in terms of blood damage, by means of finite ...
Berli, Marcelo Eduardo   +4 more
core  

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Ventricular Arrhythmia in the Left Ventricular Assist Device Patient

open access: yesJACC: Case Reports, 2021
Peter Hanna, MD, Jason S. Bradfield, MD
doaj   +1 more source

Towards the Development of a Pediatric Ventricular Assist Device

open access: yesCell Transplantation, 2006
The very limited options available to treat ventricular failure in children with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device at the University of Pittsburgh (UoP) and University of ...
Harvey S. Borovetz P.HD   +31 more
doaj   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng   +9 more
wiley   +1 more source

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