Results 131 to 140 of about 249,373 (343)

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Critical Care Transthoracic Echocardiography

Journal of Investigative Medicine High Impact Case Reports, 2014
A 70-year-old man with end-stage heart failure and a continuous-flow left ventricular assist device received repeated electrical discharges from his biventricular implantable cardiac defibrillator.
Peter Mark Schulman MD, Jill M. Gelow MD, Matthias J. Merkel MD, PhD, James O. Mudd MD, Kevin Wei MD, Michael P. Hutchens MD, MA   +5 more
doaj   +1 more source

Extracorporeal Membrane Oxygenation with Right Ventricular Assist Device for COVID-19 ARDS

Journal of Surgical Research, 2021
M. Cain, Nathan J. Smith, M. Barash, P. Simpson, L. Durham, H. Makker, Christopher J. Roberts, O. Falcucci, Dong Wang, R. Walker, Gulrayz Ahmed, Sherry‐Ann Brown, R. Nanchal, David L Joyce   +13 more
semanticscholar   +1 more source

Predictors of mid-term outcomes in patients undergoing implantation of a ventricular assist device directly after extracorporeal life support

European Journal of Cardio-Thoracic Surgery, 2018
OBJECTIVES Extracorporeal life support (ECLS) can be applied as a bridge to diagnosis and decision-making for further treatment with long-term left ventricular assist devices (LVADs).
D. Tsyganenko, T. Gromann, F. Schoenrath, M. Mueller, J. Mulzer, C. Starck, T. Krabatsch, J. Stein, V. Falk, E. Potapov   +9 more
semanticscholar   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Mechanical support of the unrepaired postinfarction ventricular septal defect with the abiomed BVS 5000 ventricular assist device [PDF]

, 2003
Louis E. Samuels, John W. Entwistle, Elena C. Holmes, Ted M. Parris, Andrew S. Wechsler   +4 more
openalex   +1 more source

Passive control of a bi-ventricular assist device : an experimental and numerical investigation [PDF]

, 2008
For the last two decades heart disease has been the highest single cause of death for the human population. With an alarming number of patients requiring heart transplant, and donations not able to satisfy the demand, treatment looks to mechanical ...
Gaddum, Nicholas Richard
core   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Towards the Development of a Pediatric Ventricular Assist Device

Cell Transplantation, 2006
The very limited options available to treat ventricular failure in children with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device at the University of Pittsburgh (UoP) and University of ...
Harvey S. Borovetz P.HD, Stephen Badylak, J. Robert Boston, Carl Johnson, Robert Kormos, Marina V. Kameneva, Marwan Simaan, Trevor A. Snyder, Hiro Tsukui, William R. Wagner, Joshua Woolley, James Antaki, Chenguang Diao, Stijn Vandenberghe, Bradley Keller, Victor Morell, Peter Wearden, Steven Webber, Jeff Gardiner, Chung M. Li, Dave Paden, Bradley Paden, Shaun Snyder, Jingchun Wu, Gill Bearnson, John A. Hawkins, Gordon Jacobs, John Kirk, Pratap Khanwilkar, Peter C. Kouretas, James Long, R. E. Shaddy   +31 more
doaj   +1 more source