Results 41 to 50 of about 43,719 (293)

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Intravenous thrombolytic therapy for patients with ventricular assist device thrombosis: An attempt to avoid reoperation

Annals of Cardiac Anaesthesia, 2016
A growing number of patients are undergoing prolonged management of advanced heart failure with the use of continuous flow left ventricular assist devices (LVADs).
Beth T Webber, Anthony L Panos, Yiliam F Rodriguez-Blanco   +2 more
doaj   +1 more source

Stroke and pump thrombosis following left ventricular assist device implantation: The impact of the implantation technique

Frontiers in Cardiovascular Medicine, 2023
ObjectivesSeveral studies have shown the potential advantage of less-invasive surgery (LIS) for left ventricular assist device (LVAD) implantation.
Michal Nozdrzykowski, Jessica-Marie Bauer, Uwe Schulz, Khalil Jawad, Christian Bireta, Sandra Eifert, Marcus Sandri, Joanna Jozwiak-Nozdrzykowska, Michael A. Borger, Diyar Saeed   +9 more
doaj   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Determinants and Outcomes of Vasoplegia Following Left Ventricular Assist Device Implantation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundVasoplegia is associated with adverse outcomes following cardiac surgery; however, its impact following left ventricular assist device implantation is largely unexplored.
Kristen M. Tecson, Brian Lima, Andy Y. Lee, Fayez S. Raza, Grace Ching, Cheng‐Han Lee, Joost Felius, Ronald D. Baxter, Sasha Still, Justin D. G. Collier, Shelley A. Hall, Susan M. Joseph   +11 more
doaj   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

Highly Sensitive Cuffless Blood Pressure Monitoring with Selective Laser‐Sintered Liquid Metal Conductors

Advanced Functional Materials, EarlyView.
A soft, compact, and cuffless system for continuous blood pressure monitoring using laser‐sintered liquid metal conductors is developed. The stretchability and sensitivity of the device enable real‐time, non‐invasive tracking of blood pressure, including recovery after exercise. This wearable device offers a practical solution for managing hypertension
Jung Jae Park, Sangwoo Hong, Yeongju Jung, Phillip Won, Carmel Majidi, Minwoo Kim, Seung Hwan Ko   +6 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Conservative Management of LVAD-Associated Ventricular Pseudoaneurysm

Methodist DeBakey Cardiovascular Journal
Left ventricular assist devices (LVAD) are surgically implanted mechanical support devices utilized with increasing frequency as a bridge to myocardial recovery, destination therapy, and heart transplantation.
Marvin Kajy, Connor C. Kerndt, Paul C. Weber, Marzia Leacche, Renzo Y. Loyaga Rendon   +4 more
doaj   +1 more source