Results 51 to 60 of about 206,338 (340)

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Impact of preoperative versus postoperative dialysis on left ventricular assist device outcomes: An analysis from the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support databaseCentral MessagePerspective

JTCVS Open, 2022
Objective: Chronic kidney disease and renal failure are common in patients being considered for left ventricular assist device support. We sought to evaluate the outcomes of patients undergoing left ventricular assist device implantation with ...
J. Hunter Mehaffey, MD, MSc, Ryan Cantor, PhD, Susan Myers, MS, Nicholas R. Teman, MD, John A. Kern, MD, Gorav Ailawadi, MD, Francis Pagani, MD, James Kirklin, MD, Kenan Yount, MD, MBA, Leora Yarboro, MD   +9 more
doaj   +1 more source

Soft Beats: A Dielectric Elastomer‐Based Ventricular Assist Device for Next‐Gen Heart Failure Management

Advanced Engineering Materials, EarlyView.
The dielectric elastomer‐based electropneumatic device (DE‐EPD) is a vacuum‐assisted ventricular assist device (VAD) that delivers high performance (85 mmHg, 6.8 L min−1) with low power consumption. Unlike traditional motor‐driven VADs, it is lightweight, quiet, energy‐efficient, and provides pulsatile flow. Validated in a simulated circulation system,
Amine Benouhiba, Armando Walter, Silje Ekroll Jahren, Francesco Clavica, Dominik Obrist, Yoan Civet, Yves Perriard   +6 more
wiley   +1 more source

Determinants and Outcomes of Vasoplegia Following Left Ventricular Assist Device Implantation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundVasoplegia is associated with adverse outcomes following cardiac surgery; however, its impact following left ventricular assist device implantation is largely unexplored.
Kristen M. Tecson, Brian Lima, Andy Y. Lee, Fayez S. Raza, Grace Ching, Cheng‐Han Lee, Joost Felius, Ronald D. Baxter, Sasha Still, Justin D. G. Collier, Shelley A. Hall, Susan M. Joseph   +11 more
doaj   +1 more source

Left Ventricular Assist Device Outflow Cannula Obstruction

JACC: Case Reports, 2020
One of the dreaded complications of left ventricular assist device implantation is mechanical obstruction of the device secondary to pump thrombosis or mechanical outflow cannula obstruction.
Majid Asawaeer, MD, Sajid Kadir, MD, Arif Albulushi, MD, Anthony W. Castleberry, MD, Yiannis S. Chatzizisis, MD, PhD   +4 more
doaj   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

Highly Sensitive Cuffless Blood Pressure Monitoring with Selective Laser‐Sintered Liquid Metal Conductors

Advanced Functional Materials, EarlyView.
A soft, compact, and cuffless system for continuous blood pressure monitoring using laser‐sintered liquid metal conductors is developed. The stretchability and sensitivity of the device enable real‐time, non‐invasive tracking of blood pressure, including recovery after exercise. This wearable device offers a practical solution for managing hypertension
Jung Jae Park, Sangwoo Hong, Yeongju Jung, Phillip Won, Carmel Majidi, Minwoo Kim, Seung Hwan Ko   +6 more
wiley   +1 more source

Supporting the “forgotten” ventricle: The evolution of percutaneous RVADs

Frontiers in Cardiovascular Medicine, 2023
Right heart failure (RHF) can occur as the result of an acute or chronic disease process and is a challenging clinical condition for surgeons and interventionalists to treat.
Les James, Deane E. Smith
doaj   +1 more source

Ventricular Assist Devices [PDF]

Journal of the American College of Cardiology, 2009
The need for mechanical assistance of the failing heart, whether acute after a myocardial infarction or permanent in patients with end-stage heart failure, has increased with improvements in medical therapy and a growing aged population. Over the past few decades, much progress has been made in the development and refinement of ventricular assist ...
Garrick C. Stewart, Sean R. Wilson, Michael M. Givertz, Gilbert H. Mudge   +3 more
openaire   +2 more sources

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source