Results 61 to 70 of about 195,940 (363)

Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients The ROADMAP Study 2-Year Results [PDF]

, 2017
OBJECTIVES The authors sought to provide the pre-specified primary endpoint of the ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) trial at 2 years ...
Boyle, Andrew J., Bruckner, Brian A., Chuang, Joyce, Estep, Jerry D., Farrar, David J., Haas, Donald C., Horstmanshof, Douglas A., Kasirajan, Vigneshwar, Lee, Sangjin, Long, James W., Milano, Carmelo A., Rogers, Joseph G., Selzman, Craig H., Shah, Keyur B., Starling, Randall C., Stehlik, Josef   +15 more
core   +2 more sources

Left Ventricular Assist Device Implantation in a Patient with Ventricular Pseudoaneurysm

The Thoracic & Cardiovascular Surgeon Reports, 2022
Background Left ventricular assist device (LVAD) implantation after contained LV rupture (pseudoaneurysm) represents a difficult surgical problem. Case Description We describe the surgical approach for such a patient.
Dejan Radakovic, Kiril Penov, Gülmisal Güder, Ivan Aleksic   +3 more
doaj   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Multi-scale simulation of thrombus formation at LVAD inlet cannula connection: Importance of Virchow's triad [PDF]

arXiv, 2020
As pump thrombosis is reduced in current-generation ventricular assist devices (VAD), adverse events such as bleeding or stroke remain at unacceptable rates. Thrombosis around the VAD inlet cannula (IC) has been highlighted as a possible source of stroke events.
arxiv  

Cardiovascular prevention and rehabilitation for patients with ventricular assist device From exercise therapy to long-term therapy Part I: exercise therapy

Monaldi Archives for Chest Disease, 2015
In the present context of an aging population, limited donor heart availability, improved reliability of mechanical cardiac support and improved patient outcomes, ventricular assist device (VAD) options to support end-stage heart failure patients are ...
Ugo Corrà, Massimo Pistono, Alessandro Mezzani, Marco Gnemmi, Franco Tarro Genta, Roberto Caruso, Pantaleo Giannuzzi   +6 more
doaj   +1 more source

Stroke and pump thrombosis following left ventricular assist device implantation: The impact of the implantation technique

Frontiers in Cardiovascular Medicine, 2023
ObjectivesSeveral studies have shown the potential advantage of less-invasive surgery (LIS) for left ventricular assist device (LVAD) implantation.
Michal Nozdrzykowski, Jessica-Marie Bauer, Uwe Schulz, Khalil Jawad, Christian Bireta, Sandra Eifert, Marcus Sandri, Joanna Jozwiak-Nozdrzykowska, Michael A. Borger, Diyar Saeed   +9 more
doaj   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

Advanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang, Zilu Xu, Feiyang Zheng, Dongcheng Yang, Kaige Xu, Ming Ke, Xiao Zhou, Xiaohan Zhang, Ju Tan, Yong Liu, Yansha Hao, Malcolm Xing, Chuhong Zhu   +12 more
wiley   +1 more source

In Vitro and In Silico Characterization of the Aggregation of Thrombi on Ventricular Assist Device Cannula [PDF]

arXiv, 2023
The unacceptably high stroke rate of HeartMate III VAD without signs of adherent pump thrombosis is hypothesized to be the result of the thrombi originating on the inflow cannula, ingesting and ejecting emboli from the VAD. Therefore, inflow cannula thrombosis has been an emerging focus.
arxiv  

Ventricular Assist Devices [PDF]

Journal of the American College of Cardiology, 2009
The need for mechanical assistance of the failing heart, whether acute after a myocardial infarction or permanent in patients with end-stage heart failure, has increased with improvements in medical therapy and a growing aged population. Over the past few decades, much progress has been made in the development and refinement of ventricular assist ...
Garrick C. Stewart, Sean R. Wilson, Michael M. Givertz, Gilbert H. Mudge   +3 more
openaire   +2 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source