Results 81 to 90 of about 184,386 (363)
Advanced Science, EarlyView.Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng +11 more
wiley +1 more source
Annals of Cardiac Anaesthesia, 2009 Propofol and isoflurane may be used during fast track anesthesia for off-pump bypass, where transient ischemia is common. The purpose of this study was to compare the effects of propofol vs isoflurane in a porcine model of acute coronary occlusion ...
Urdaneta Felipe +3 more
doaj
Advanced Science, EarlyView.Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li +21 more
wiley +1 more source
A non-intrusive data-driven ROM framework for hemodynamics problems [PDF]
, 2020 Reduced order modeling (ROM) techniques are numerical methods that approximate the solution of parametric partial differential equation (PDE) by properly combining the high-fidelity solutions of the problem obtained for several configurations, i.e. for several properly chosen values of the physical/geometrical parameters characterizing the problem.
arxiv +1 more source
Ventricular assist devices for all? [PDF]
European Journal of Cardio-Thoracic Surgery, 2012 In the past 5 years, the numbers of ventricular assist device (VAD) systems implanted worldwide have increased exponentially. Thus, since the introduction of the HeartMate II LVAD by Thoratec (Thoratec Inc., Pleasanton, CA, USA) over 10 000 of these pumps have been implanted.
Christoph Knosalla +3 more
openaire +3 more sources
Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices
Advanced Science, EarlyView.In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley +1 more source
Epistaxis Rates and Health Care Utilization in Patients With a Ventricular Assist Device
OTO OpenObjective Identify baseline epistaxis rates and epistaxis‐related health care utilization trends in the ventricular assist device (VAD) population.
Eric Rohe +4 more
doaj +1 more source
The Variational Multiscale Formulation for the Fully-Implicit Log-Morphology Equation as a Tensor-Based Blood Damage Model [PDF]
, 2019 We derive a variational multiscale (VMS) finite element formulation for a viscoelastic, tensor-based blood damage model. The tensor equation is numerically stabilized by a logarithmic shape tensor description that prevents unphysical, negative eigenvalues.
arxiv +1 more source
Microneedles at the Forefront of Next Generation Theranostics
Advanced Science, EarlyView.The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang +8 more
wiley +1 more source
Postoperative care of 14 patients with left ventricular assist devices: a case series
Journal of International Medical ResearchA left ventricular assist device is a mechanical device that is surgically implanted in the heart to partially or completely replace the function of the heart.
Shenmin Wan +3 more
doaj +1 more source