Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Advanced Materials, EarlyView.Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Predicting Bleeding and Thrombosis Complications in Patients with Continuous Flow Left Ventricular Assist Devices [PDF]
, 2020 Background: Left ventricular assist device (LVAD) therapy has been proven to relieve heart failure symptoms and improve survival, but is not devoid of bleeding and/or thrombotic complications.
Cook, Aaron +6 more
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A Short Review of Advances in the Modelling of Blood Rheology and Clot Formation [PDF]
, 2017 Several advances have taken place since the early 2000s in the field of blood flow modelling. These advances have been driven by the development of assist devices such as Left Ventricular Assist Devices (LVADs), etc., and by the acceptance of in silico ...
Mohan, Anand, Rajagopal, K R
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The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, EarlyView.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review
Journal of the Practice of Cardiovascular SciencesAdvanced heart failure (AHF) is a major problem with an aging population and profound unmet needs. While heart transplant offers the most definitive solution, it is largely unavailable for most and mandates a long waiting period.
Devesh Kumar, Sandeep Seth, Rajiv Narang
doaj +1 more source
Ophthalmic Surgery in Patients with Left Ventricular Assist Devices
Case Reports in Ophthalmological Medicine, 2019 The newer generation of left ventricular assist devices (LVADs) are commonly used as destination therapy; these devices have demonstrated improved outcomes and increased survival.
George A. Dumas +2 more
doaj +1 more source
Computer simulation of platelet activation in a pulsatile ventricular assist device, through finite elements and a simplified geometry [PDF]
, 2017 Ventricular assist devices are a technological solution for patients who suffer from cardiac insufficiency and await a transplant. In this work, a new design of an implantable pulsatile blood pump is analyzed in terms of blood damage, by means of finite ...
Berli, Marcelo Eduardo +4 more
core
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Advanced Materials, EarlyView.Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
Prognostic impact of implantable cardioverter defibrillators and associated adverse events in patients with continuous flow left ventricular assist devices [PDF]
, 2023 Jonas Pausch +8 more
openalex +1 more source
Numerical coupling of fluid and structure in cardiac flow and devices [PDF]
, 2006 Numerical simulations are a powerful tool in investigation of flow and structure dynamics in biological systems and in the design of biomedical devices.
Avrahami, Idit
core +1 more source