Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Advanced Science, EarlyView.Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu +6 more
wiley +1 more source
Effect of obstructive sleep apnea syndrome on left ventricular function
Egyptian Journal of Chest Disease and Tuberculosis, 2012 Background: The link between OSAS, left ventricular dysfunction, and congestive heart failure is less known, although OSAS is frequent in both systolic and diastolic heart failure patients.
Mohamad G. El-Kholly +3 more
doaj +1 more source
Simulation of Cardiac Flow: Analysis of Geometry Simplification [PDF]
arXiv, 2019 Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with the initiation and progression of many CVDs. Thus, understanding and evaluating the flow pattern inside a patient LV
arxiv
Coronary endothelial dysfunction in patients with acute-onset idiopathic dilated cardiomyopathy [PDF]
, 1998 Objectives. This study sought to determine whether coronary endothelial dysfunction exists in patients with acute-onset idiopathic dilated cardiomyopathy (DCM) and to explore its relation to recovery of left ventricular systolic function in this patient ...
Castaño, Hugo H +8 more
core +1 more source
Prospective evaluation of smartwatch-enabled detection of left ventricular dysfunction
Nature Network Boston, 2022 Z. Attia +15 more
semanticscholar +1 more source
Advanced Science, EarlyView.Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong +15 more
wiley +1 more source
Mirror image: Recurrent Takotsubo cardiomyopathy with variable regional involvement [PDF]
, 2019 Takotsubo cardiomyopathy (TCM), a stress-induced cardiomyopathy, is a well-recognised cause of left ventricular dysfunction. It commonly presents similar to acute coronary syndrome with chest, dyspnoea, and electrocardiographic changes consistent with ...
Fan, Jerry +3 more
core +2 more sources
Advanced Science, EarlyView.This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao +17 more
wiley +1 more source
An effect of left ventricular hypertrophy on mild-to-moderate left ventricular diastolic dysfunction
Hellenic Journal of Cardiology, 2016 Objectives: Left ventricular diastolic dysfunction (LVDD) is associated with a variety of medical conditions. Left ventricular hypertrophy (LVH) is one of the most common abnormalities that induce LVDD.
Sharma Kattel, MD +4 more
doaj +1 more source
The selective bradycardic effects of zatebradine (UL-FS 49) do not adversely affect left ventricular function in conscious pigs with chronic coronary artery occlusion [PDF]
, 1992 Summary This study was designed to test whether the selective bradycardic effects of zatebradine (UL-FS 49) were altered in the setting of chronic mild left ventricular dysfunction secondary to a myocardial infarction.
Giessen, W.J. (Wim) van der +2 more
core +1 more source