Results 81 to 90 of about 743,550 (357)

Reduced-order modeling of left ventricular flow subject to aortic valve regurgitation [PDF]

Physics of Fluids, 31(3), 031901 (2019), 2019
The present focus of heart flow studies is largely based on flow within the left ventricle and how this flow changes when subject to disease. However, despite recent advancements, a simple tractable model of even healthy left ventricular flow has not been produced and made available.
arxiv   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Value of the radiological study of the thorax for diagnosing left ventricular dysfunction in Chagas' disease

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To determine the value of the radiological study of the thorax for diagnosing left ventricular dilation and left ventricular systolic dysfunction in patients with Chagas' disease.
Perez Amanda Arantes, Ribeiro Antonio Luiz Pinho, Barros Márcio Vinícius Lins, Sousa Marcos Roberto de, Bittencourt Roberto José, Machado Fernando Santana, Rocha Manoel Otávio Costa   +6 more
doaj  

Severe transient left ventricular dysfunction induced by thyrotoxicosis [PDF]

, 2011
We report on a 44-year-old woman presenting with chest pain and dyspnoea without previous stress-related events. By means of echocardiography severe left ventricular dysfunction and wall motion abnormalities resembling stress-induced cardiomyopathy (Tako
AR Lyon, G Cini, JC Forfar, JD Walker, K Ojamaa, M Froeschl   +5 more
core   +2 more sources

Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

Cardiovascular Research, 2018
Aims More than 50% of patients with heart failure have preserved ejection fraction characterized by diastolic dysfunction. The prevalance of diastolic dysfunction is higher in females and associates with multiple comorbidities such as hypertension (HT ...
O. Sorop, I. Heinonen, Matthijs van Kranenburg, J. van de Wouw, Vincent J. de Beer, Isabel T N Nguyen, Y. Octavia, Richard W. B. van Duin, K. Stam, R. V. van Geuns, P. Wielopolski, G. Krestin, A. H. van den Meiracker, R. Verjans, M. van Bilsen, A. Danser, W. Paulus, Caroline Cheng, W. Linke, J. Joles, M. Verhaar, J. van der Velden, D. Merkus, D. Duncker   +23 more
semanticscholar   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Indications for immediate angiotensin-converting enzyme inhibition in patients with acute myocardial infarction [PDF]

, 1995
When initiated a few days after myocardial infarction, angiotensin-converting enzyme inhibition exerts beneficial effects on survival and morbidity in patients with asymptomatic left ventricular systolic dysfunction or symptomatic heart failure.
Hochman, Judith S., LeJemtel, Thierry H., Sonnenblick, Edmund H.   +2 more
core   +1 more source

Cardiac tamponade in left ventricular dysfunction. [PDF]

Circulation, 1990
Echocardiographic and hemodynamic data were measured in closed-chest dogs during graded cardiac tamponade (pericardial pressure 5, 10, and 15 mm Hg) before and after production of diffuse ischemic left ventricular dysfunction. Left ventricular dysfunction was produced by intracoronary injection of nonradioactive microspheres (54 +/- 3.9 mm diameter ...
Marjorie Gabel, Brian D. Hoit, Noble O. Fowler   +2 more
openaire   +3 more sources

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

Advanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang, Dajun Li, Xiao Ying Li, Weizhao Lu, Huini Ding, Chengyan Qi, Xuan Wang, Jing Shen, Yafei Chi, Tiantian Li, Michelle M. Dunk, Yu An, Hongmei Huang, Kang Yu, Weili Xu, Rong Xiao, Yuandi Xi   +16 more
wiley   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source